Abstract:Objective:We evaluated the clinical efficacy and safety of 2 micron continuous-wave laser vaporesection in treating senile patients with obstructive benign prostatic hyperplasia (BPH). Methods:106 senile patients with BPH were enrolled, whose age are all more than 70 years old. All the patients with obstructive BPH received analyzed using a 70 W 2-micron continuous-wave laser between July 2010 and July 2012. The mean (range) age of the patients was (82.8±9.6) (70-89) years. Resection time, bladder irrigation time and catheter time were measured perioperatively and the following variables were assessed before and 24 hours after vaporesection: bleeding volume and electrolyte changes and the safety perioperatively. IPSS、OABSS and QOL of all the patients were recorded before and 3 months after operation. Results:The mean resection time was (69.0±12.4)(32-128) minutes. The time of bladder irrigation is (-23.0±5.1) (8-28)h. The mean catheter time was (3.6±0.7) (3-5) days. Before and after operation the patients with electrolyte disturbance and bleeding volume change was not observed (P>0.05). No severe cardiovascular、cerebral and pulmonary complications occurred during perioperative period. all the index including IPSS、OABSS、QOL were obviously improved (P<0.05) after treatment 3 months later. Conclusions:2 micron continuous-wave laser of treatment senile patients with BPH has great advantages by safty of peroperative period decreasingresection time, bladder irrigation time and catheter time and the obvious clinical efficacy.
[1]张祥华.前列腺增生诊断治疗指南. 见:那彦群,孙光.中国泌尿外科疾病治疗诊断指南.北京:人民卫生出版社, 2009:103. [2]洪宝发,符伟军,蔡伟,等.经尿道选择性绿激光前列腺汽化术治疗高龄高危良性前列腺增生. 中华泌尿外科杂志,2006,27(1): 43-45. [3]鹿尔驯.新型激光在前列腺外科中的应用.中华外科杂志,2007, 45(14):964-966. [4]Wendt-Nordahl G, Huckele S, Honeck P, et al. Systematic evaluation of a recently introduced 2-microm continuous-wave thulium laser for vaporesection of the prostate. J Endourol, 2008,22(5):1041-1045. [5]Chang Q, Bai ZY. The experience of electro-vaporization of prostate for the older patients with spinal-epidural anesthesia. Minimally Invasive Medicine, 2009, 4(2): 149-151. [6]Xia SJ, Zhuo J, Sun XW, et al. Thulium laser versus standard transurethral resection of the prostate: a randomized prospective trial. Eur Urol, 2008,53(2):382-389. [7]Fu WJ, Hong BF, Yang Y, et al. Vaporesection for managing benign prostatic hyperplasia using a 2-microm continuous-wave laser: a prospective trial with 1-year follow-up. BJU Int, 2009,103(3):352-356. [8]Fu WJ, Hong BF, Yang Y, et al. Two micron continuous wave laser vaporesection for the treatment of benign prostatic hyperplasia. Asian J Androl, 2008,10(2):341-342. [9]Xia SJ. Two-micron (thulium) laser resection of the prostate-tangerine technique: a new method for BPH treatment. Asian J Androl, 2009,11(3):277-281.