Abstract：Objective:To study the efficacy and safety of 1 470 nm diode laser for the treatment of benign prostatic hyperplasia (BPH). Methods:A total of 87 patients underwent vaporization of the prostate using 1 470 nm diode laser. The mean operative time, blood loss, the international prostate symptom score (IPSS), the score of life quality, bladder residual urine volume, flow rate and indwelling catheterization time were recorded and analyzed. Results:All procedures were successfully performed by one operation. The operation time was (72±31) min, and blood loss (23±11) mL. No case needed blood transfusion, and there was no TURP-related syndrome. The mean indwelling catheterization time was (35±20) h. Eighty-seven cases were followed up for 3 to 12 months. The IPSS was decreased from preoperative (27.3±2.4) to (5.8±1.6). The QOL was decreased from preoperative (4.8±1.1) to (1.7±0.4). The maximum flow rate was increased from preoperative (6.3±3.2) mL/s to (19.8±2.1) mL/s. The residual urine volume was decreased from preoperative (86.7±139.5) mL to (29.3±5.1) mL. All the differences were statistically significant (P<0.05). Conclusions:1 470 nm diode laser is safe, efficacious and minimally invasive for the patients of BPH.
[1]Madersbacher S, Alivizatos G, Nordling J, et al. EAU 2004 guidelines on assessment, therapy and follow-up of men with lower urinary tract symptoms suggestive of benign prostatic obstruction (BPH guidelines). Eur Urol, 2004, 46(5):547-554. [2]Yu X, Elliott SP, Wilt TJ, et al. Practice patterns in benign prostatic hyperplasia surgical therapy: the dramatic increase in minimally invasive technologies. J Urol, 2008,180(1):241-245. [3]Tan A, Liao C, Mo Z, et al. Meta-analysis of holmium laser enucleation versus transurethral resection of the prostate for symptomatic prostatic obstruction. Br J Surg, 2007, 94(10):1201-1208. [4]Bruyère F, Puichaud A, Pereira H, et al. Influence of photoselective vaporization of the prostate on sexual function: results of a prospective analysis of 149 patients with long-term follow-up. Eur Urol, 2010, 58(2):207-211. [5]邵晋凯,王毓斌,吕永安,等.2微米激光前列腺剜除术与经尿道前列腺电切术治疗良性前列腺增生的疗效比较.中华泌尿外科杂志,2012,50(2):131-134. [6]葛沈林,朱建,解吕中.绿激光选择性汽化术与传统电切术对前列腺增生的治疗效果比较.微创泌尿外科杂志,2013,2(5):340-343. [7]Seitz M, Sroka R, Gratzke C, et al. The diode laser: a novel side-firing approach for laser vaporisation of the human prostate--immediate efficacy and 1-year follow-up. Eur Urol, 2007,52(6):1717-1722. [8]Seitz M, Ruszat R, Bayer T, et al. Ex vivo and in vivo investigations of the novel 1,470 nm diode laser for potential treatment of benign prostatic enlargement. Lasers Med Sci, 2009, 24(3):419-424. [9]杨勇.激光汽化术在良性前列腺增生症治疗中的应用.中华外科杂志, 2013,51(2):99-103. [10]孙颖浩, 杨波.钬激光在泌尿外科中的应用.中华泌尿外科杂志, 2005,26(1):62-64. [11]夏术阶, 张沂南, 鲁军, 等.铥激光“剥橘”式切除术治疗良性前列腺增生症.中华医学杂志, 2005,85(45):3225-3228.
