Abstract：Objective: To evaluate the safety and effectiveness of 1 470 nm laser vaporization of the prostate for the treatment of benign prostatic hyperplasia (BPH). Methods: A total of 156 patients with BPH were included in the present study. Operative time, laser emission time, laser energy consumption, blood loss, bladder irrigation time, catheter removal time and peri-operative complications were recorded. Prostate specific antigen (PSA), post-void residual volume (PVR), International Prostatic Symptom score (IPSS), quality of life (QOL) score and maximum flow rates (Qmax) were measured preoperatively and 3 months postoperatively. Results: All of the 156 cases were operated on successfully, and none of them converted to TURP or open surgery. The mean operative time, laser emission time, laser energy consumption, blood loss, bladder irrigation time and catheter removal were (55.4±24.1) min, (34.7±14.3) min, (249.4±118.2) kJ, (26.8±13.6) mL, (11.9±5.3) h and (2.7±0.9) days respectively. No significant reductions were found in serum sodium levels (P>0.05). No severe complications were observed. Clinical outcomes (PSA, PVR, IPSS, QOL score and Qmax) showed immediate improvement from baseline (P<0.05). Conclusions: The results of our study show that 1 470 nm laser vaporization has the advantages of high vaporizing efficiency, low morbidity, and reliable recent effect. This procedure could be applied in a safe and effective manner for the treatment of BPH.
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