Clinical effect of Moses holmium laser combined with flexible ureteroscope lithotrity for the 2~3 cm renal calculus
Mai Haixing, Zuo Shidong, Gu Liangyou, Chen Zhiqiang, Zhang Yongjie, Lu Yongliang, Chen Weihao, Kong Lingsheng, Zhang Xu*
1Department of Urology, the First Medical Centre, Chinese PLA General Hospital; 2Department of Urology, the Fifth Medical Centre, Chinese PLA General Hospital; 3Department of Urology, the Third Medical Centre, Chinese PLA General Hospital
Abstract：Objective： To compare the safety and effectiveness of Moses holmium laser and general holmium laser combined with flexible ureteroscope lithotrity （FURL） for the 2~3 cm renal calculus. Methods： The clinical data of 32 patients with 2~3 cm renal calculus treated by FURL from January 2021 to June 2021 were retrospectively analyzed. The patients were divided into Moses holmium laser + FURL group and holmium laser + FURL group,with 16 patients in each group. There were 16 cases in the Moses holmium laser + FURL group, including 12 males and 4 females, with an average age of 42.9±15.0 years. There were 16 cases in the holmium laser + FURL group, including 11 males and 5 females, with an average age of 45.2±15.8 years. Results： There was no statistically significant difference between the two groups in baseline data, such as the stone size, density and load （P>0.05）. The operation time in the Moses holmium laser + FURL group was significantly shorter than in the holmium laser + FURL group （35.3±10.1 vs. 49.5±13.5 min, P<0.05）. There was significant difference in the incidence of secondary operations in the postoperative follow-up period between the Moses holmium laser + FURL group and the holmium laser + FURL group （0.0% vs. 25%, P<0.05）. The final stone removal rate was 100% in both two groups after 28 days. There were 2 cases of fever （>38°C） in the holmium laser + FURL group, which was significantly more than the Moses holmium laser + FURL group. Conclusion： Moses holmium laser + FURL is beneficial to reduce postoperative complications and improve the efficiency of stone removal for the 2~3 cm renal calculus. The rate of secondary surgery is low and its value for clinical dissemination can be further determined by follow-up studies with large sample sizes.
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