Abstract：Objective: To explore the risk factors of urinary tract infection after percutaneous nephrolithotomy （PCNL） in complicated renal calculi. Methods： A retrospective analysis was performed on 236 patients with complicated kidney stones after the first-stage PCNL operation in the Panyu District of the Second Affiliated Hospital of Guangzhou Medical University from July 2016 to July 2019. According to whether the patients were complicated with urinary tract infection, they were divided into urinary tract infection group （n = 86） and non-urinary tract infection group （n = 150）. The risk factors of postoperative urinary tract infection were analyzed by single factor and multivariate logistic. Results： Univariate analysis results showed that concomitant renal dysfunction, diabetes, preoperative urinary tract infection, preoperative blood glucose level, operation time （> 100 min）, intraoperative channel type （multi-channel）, stone load （>1 000 mm2）, postoperative indwelling catheterization time （> 7 d） were risk factors of urinary tract infection after PCNL （P < 0.05）. The results of multivariate logistic regression analysis showed that concomitant renal dysfunction [OR = 9.134, 95%CI （0.206-0.691）, P = 0.005], stone burden [OR = 4.634, 95%CI （1.421-2.157）, P < 0.001], preoperative urinary tract infection [OR = 3.278, 95%CI （1.602-2.776）, P <0.001], preoperative blood glucose level [OR = 4.389, 95%CI （2.034-2.634）, P = 0.016] were independent risk factors of urinary tract infection after PCNL. Conclusion： Concomitant renal dysfunction, stone burden, preoperative urinary tract infection, and preoperative blood glucose level are independent risk factors of urinary tract infection after PCNL in complicated renal calculi.
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