Abstract：Objective: To investigate the risk factors of secondary hemorrhage after transurethral resection of the prostate (TURP). Methods: The clinical data of 339 patients who underwent TURP were retrospectively analyzed. The related factors of secondary hemorrhage after TURP were analyzed using multivariate Logistic regression analysis. Results: Secondary hemorrhage occurred in 31 cases of total 339 patients, with the incidence of 9.14%. The univariate analysis showed that increase of hemorrhage incidence was significantly correlated with a large volume of prostate, diabetes, hypertension, urinary tract infection within 1 week preoperatively, indwelling catheters within 1 week preoperatively and no using of epidural analgesia pump postoperatively. The rates were 14.04%, 29.17%, 12.99%, 17.76%, 13.91% and 22.03%, respectively. The differences were statistically significant (P<0.05 or 0.01). Multivariate Logistic regression analysis showed that the volume of the prostate (OR=4.14), urinary tract infection within 1 week preoperatively (OR=2.80) and diabetes mellitus (OR=4.81) were independent risk factors of secondary hemorrhage after TURP and the use of epidural analgesia pump (OR=0.46) was a protective factor. Conclusions: A large volume of prostate, urinary tract infection within 1 week preoperatively and diabetes increase the risk of the secondary hemorrhage after TURP, and the use of epidural analgesia pump can reduce the risk of secondary hemorrhage.
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