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微创泌尿外科杂志  2015, Vol. 4 Issue (5): 289-291    
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二次电切治疗非肌层浸润性膀胱癌的临床研究
何泉芳1,唐华2
1福建中医药大学 350000 福州;
2福建中医药大学附属三明第二医院泌尿外科
Clinical research of a second transurethral resection for non muscle-invasive bladder cancer
He Quanfang1, Tang Hua2
1Fujian University of Traditional Chinese Medicine, Fuzhou 350000, China; 2Department of Urology, Second Hospital of Sanming, Affiliated Fujian University of Traditional Chinese Medicine
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摘要 目的:探讨非肌层浸润性膀胱癌患者行二次经尿道电切术(ReTUR)治疗的临床意义。方法:所有非肌层浸润性膀胱癌患者62例分为2组,首次经尿道膀胱肿瘤电切术(TURBT)后4周内行ReTUR 30例为实验组;以同期单次行TURBT的32例患者为对照组。两组术后均以吡柔比星膀胱灌注化疗处理,观察两组肿瘤复发及进展情况。结果:随访2年期间内,实验组有8例(26.7%)肿瘤复发,3例(10%)肿瘤进展;对照组有19例(59.4%)肿瘤复发,7例(21.9%)肿瘤进展。实验组患者的肿瘤复发率较对照组复发率显著降低(P<0.05);两组进展为肌层浸润性膀胱癌的差异无统计学意义(P>0.05)。结论:二次经尿道电切术可以降低非肌层浸润性膀胱癌的术后复发率,但不能减少发展为肌层浸润性膀胱癌的风险。
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何泉芳
唐华
关键词 膀胱癌二次经尿道肿瘤电切复发率吡柔比星    
AbstractObjective: To investigate the effect of repeat transurethral resection for non muscle-invasive bladder cancer. Methods: All 62 cases of non muscle-invasive bladder cancer were divided into 2 groups: 30 in experimental group treated with second resection after the first transurethral resection 4 weeks later; the control group (n=32) given single transurethral resection of bladder tumor (TURBT) in the same period. All patients were treated with pirarubicin bladder irrigation after the TURBT in the two groups. Tumor recurrence rate and progression rate were observed. Results: Tumor recurred in 8 patients in the experimental group and 19 in the control group during the follow-up period of two years. There was a significant reduction in the recurrence rate in the experimental grooup compared with the control group. There was no significant difference in progression rate between the two group (10% vs. 21.9%, P>0.05). Conclusions: Second transurethral resection reduces the recurrence rate, but did not reduce the risk of tumor progression in non muscle-invasive bladder cancer.
Key wordsurinary bladder neoplasms    second transurethral resection    recurrence rate    pirarubicin
收稿日期: 2015-06-27     
ZTFLH:  R737.14  
通讯作者: 唐华     E-mail: th.1115@163.com
引用本文:   
何泉芳,唐华. 二次电切治疗非肌层浸润性膀胱癌的临床研究[J]. 微创泌尿外科杂志, 2015, 4(5): 289-291.
He Quanfang, Tang Hua. Clinical research of a second transurethral resection for non muscle-invasive bladder cancer. JOURNAL OF MINIMALLY INVASIVE UROLOGY, 2015, 4(5): 289-291.
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