Abstract：Objective: To study the diagnosis and treatment of multilocular cystic renal cell carcinoma. Methods: The clinical data of manifestations, Diagnosis, Surgical approaches and Pathology of 26 cases with multilocular cystic renal cell carcinoma treated from January 2008 to February 2014 were analyzed retrospectively. Results: Postoperative pathological examination of all 26 cases showed multilocular cystic renal cell carcinoma. Open surgery for 4 cases (laparoscopic surgery with open surgery convertion for 2 cases), minimally invasive surgery for 22 cases ( laparoscopic surgery for 4 cases, retroperitoneal laparoscopic surgery for 17 cases, robot assisted laparoscopic surgery for 1 case); partial nephrectomy for 14 cases, radical nephrectomy for 12 cases. All of the 26 cases were followed up. The mean follow-up period is 43.8 months, there was no recurrence or metastasis observed. Conclusions: Multilocular cystic renal cell carcinoma is characterized as lower malignant potential with a favorable prognosis. Imaging plays an important role in the early diagnosis of cystic renal cell carcinoma. Surgery is the preferred treatment for multilocular cystic renal cell carcinoma.
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