Abstract:Objective:To evaluate safety and efficacy of the new bidirectional barbed free-knot absorbable suture (QUILL SRS) in laparoscopic partial nephrectomy of hilar tumors. Methods:The clinical data of 10cases of laparoscopic partial nephrectomy for renal hilar tumors were retrospectively analyzed. All cases were given QUILL SRS to suture the kidney. There were 6 males and 4 femaleswithage ranging from 27 to 69 years (mean [47.5±19.3] years). Tumor diameter was 1.5-4.7 cm (average [3.2±1.4] cm). There were 7 cases of ventral tumor and 3 cases of dorsal tumor. Nine cases suffered from single tumor and one from bilateral renal tumor. All patients were fallen into T1N0M0 by AJCC TNM staging preoperatively. Results:LPN was successfully operated on 10 cases. Operation time was 57-107 min with an average of (87.2±20.4) min. Intraoperative blood loss was 30-180 mL with an average of (55.0±42.8) mL, renal artery occlusion (warm ischemia) time was 11-32 min with an average of (23.3±12.6) min. Suture time was 8-21 min with an average of (14.3±9.7) min. Postoperative hospital stay was 5-8 d with an average of (6.5±1.3) d. No renal pedicle vascular injury, secondary bleeding, urine leakage and other complications occurred. Postoperative bleeding and hematuria occurred in 1 case, and recovered after conservative treatment. Pathological findings were all Renal cell carcinoma was pathologically confirmed, and surgical margins were negative. After follow-up for 1-6 months, no local recurrence and distant metastasis occurred. Suture time and warm ischemia time were significantly shorter, the operation time was shorter, and secondary hemorrhage rate was less in LPN than in control group. Conclusions:Use of new bidirectional barbed free-knot suture in LPN for hilar tumors can significantly reduce the suture time and warm ischemia time, which is conducive to the protection of renal function with good safety and feasibility.
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