Abstract：Objective： To analyze the risk factors of urosepsis after retrograde intrarenal surgery （RIRS）, and to construct a nomogram prediction model. Methods ： A total of 400 patients who underwent RIRS in our hospital from January 2018 to December 2021 were collected as the research objects. According to the presence or absence of urosepsis after RIRS, the patients were separated into the group with urosepsis after RIRS （n=30） and the group without urosepsis after RIRS （n=370）. Multivariate logistic regression was performed to analyze the risk factors of urosepsis after RIRS. R software was performed to build a nomogram model for predicting the risk of urosepsis complications after RIRS, and the ROC curve and calibration curve were performed to verify the nomogram model. Results： Logistic regression analysis showed that female, diabetes, stone diameter ≥2 cm, and ipsilateral stone obstruction were independent risk factors for urosepsis after RIRS （P<0.05）. The nomogram model for predicting urosepsis after RIRS was validated as follows： the area under the ROC curve was 0.888 （95% CI： 0.840-0.937）; the slope of the calibration curve was close to 1, and the H-L goodness-of-fit test χ2=5.760, P=0.330. Conclusion： Female, diabetic, stone diameter ≥2 cm, and ipsilateral stone obstruction are independent risk factors for urosepsis after RIRS. The nomogram model constructed based on the above indicators has good predictive performance for urosepsis after RIRS.
殷金成, 顾燕青, 唐新宇, 郭宗保, 刘洪新. 输尿管软镜下钬激光碎石取石术后并发尿脓毒血症危险因素分析及列线图预测模型[J]. 微创泌尿外科杂志, 2022, 11(4): 239-245.
Yin Jincheng, Gu Yanqing, Tang Xinyu, Guo Zongbao, Liu Hongxin. Risk factors for urosepsis after retrograde intrarenal surgery and construction of a nomogram prediction model. JOURNAL OF MINIMALLY INVASIVE UROLOGY, 2022, 11(4): 239-245.
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