Abstract：Objective： To summarize the applied value of “ZebraScope” in the treatment of upper urinary tract calculi. Methods： The clinical data of 81 patients with upper urinary tract calculi admitted to our hospital from April to October 2020 were retrospectively analyzed. All patients underwent “zebra” flexible holmium laser lithotripsy with a Fr5 or Fr6 ureteral stent for 4 weeks. Results： A total of 80 patients were successfully operated by soft endoscope, and 5 patients had difficulty in sheath placement. Among them, 3 cases were successfully operated by post-sheath expansion, 2 cases were given lithotripsy by bare endoscope without sheath expansion, and 1 case receiving lower calyceal stone lithotripsy was converted to percutaneous nephroscope. The operative time ranged from 35 to 112 （45±7） min. There were 13 cases of postoperative fever and no adverse complications such as low back pain, subcapsular hematoma, ureteral perforation, ureteral avulsion and severe hemorrhage. The postoperative hospital stay ranged from 3 to 7 （3.8±1.2） days. Stone formation clearance rate was 95.4% at 2nd month after surgery. Conclusion： “Zebra” disposable flexible ureteroscopy is safe, effective and cost-effective in the treatment of upper urinary tract calculi （≤ 2 cm in diameter）. Indwelling ureteral stent for 1 week before surgery can improve the success rate of sheath placement and reduce surgical complications. The use of an open perfusion channel can reduce intrapelvic pressure.
