内镜下腹股沟淋巴结清扫术联合负压封闭引流在阴茎癌中的疗效观察

doi:10.19558/j.cnki.10-1020/r.2020.02.015

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摘要 目的：探讨阴茎癌原发病灶切除术后采取经下腹皮下通路内镜下腹股沟淋巴结整块清扫术（HS-VEIL）联合持续闭合负压引流技术(VSD)的有效性和安全性。方法：回顾性分析2013年3月–2019年6月采取HS-VEIL和开放腹股沟淋巴结清扫术（OIL）治疗24例阴茎癌患者的临床资料,其中接受HS-VEIL和OIL各12例,所有患者均在切除原发病灶后行双侧腹股沟淋巴结清扫术,HS-VEIL术后采取VSD引流技术。观察两组患者相关技术指标、阳性淋巴结检出率、并发症发生率以及随访情况,评价其手术效果。结果：HS-VEIL组在术中出血量、术后引流时间、术后住院时间、切口感染等技术指标上明显低于OIL组,差异有统计学意义（P<0.05）。结论：HS-VEIL联合VSD技术在阴茎癌中的疗效肯定,不仅可以达到与开放手术一致的控瘤效果,同时具有创伤小、恢复快、并发症发生率低等明显优势,值得临床推广应用。

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	陈冰
	虞河江
	胡振兴
	胡庆新
	王晓锋

关键词 ：阴茎癌, 内镜下腹股沟淋巴结清扫术, 开放腹股沟淋巴结清扫术, 持续负压封闭引流

Abstract：Objective： To explore the effectiveness and safety of hypogastric subcutaneous pathway video endoscopic inguinal lymphadenectomy (HS-VEIL) combined with vacuum sealing drainage (VSD) in the treatment of penile cancer. Method： A retrospective analysis was conducted on 24 patients with penile cancer treated with HS-VEIL or open inguinal lymphadenectomy (OIL) between March 2013 and June 2019, and bilateral inguinal lymphadenectomy was performed on all patients after resection of the primary lesion. Among them, there were 12 cases of HS-VEIL and 12 cases of OIL. VSD technique after HS-VEIL, relevant technical indices, detection rate of positive lymph nodes, incidence of complications as well as follow-up conditions of 24 patients were observed for the assessment of operative effectiveness. Results： As compared with OIL group, the post-operative blood loss, the post-operative drainage time, the post-operative hospital stay, and the incidence of the incision infection were significantly reduced in HS-VEIL group (all P < 0.05). Conclusion： The curative effectiveness of the combination of HS-VEIL and VSD in the treatment of penile cancer is unequivocally confirmed, which can not only achieve the same tumor control effects as open surgery, but also has obvious advantages of small trauma, rapid recovery and low complications, which is worthy of clinical promotion and application.

Key words： penile cancer video endoscopic inguinal lymphadenectomy open inguinal lymphadenectomy vacuum sealing drainage

收稿日期: 2019-05-13

ZTFLH:

R737.27

通讯作者: 王晓锋, 1908059013@qq.com

引用本文:

陈冰, 虞河江, 胡振兴, 胡庆新, 王晓锋. 内镜下腹股沟淋巴结清扫术联合负压封闭引流在阴茎癌中的疗效观察[J]. 微创泌尿外科杂志, 2020, 9(2): 139-144.
CHEN Bing, YU Hejiang, HU Zhenxing, HU Qingxin, WANG Xiaofeng. Curative effectiveness of hypogastric subcutaneous pathway video endoscopic inguinal lymphadenectomy combined with vacuum sealing drainage in the treatment of penile cancer. JOURNAL OF MINIMALLY INVASIVE UROLOGY, 2020, 9(2): 139-144.

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http://journal20.magtechjournal.com/Jwk_zgmnwk/CN/abstract/abstract1587.shtml 或 http://journal20.magtechjournal.com/Jwk_zgmnwk/CN/Y2020/V9/I2/139

[1] KRISTIANSEN S, SVENSSON, DREVIN L, et al.Risk Factors for Penile Intraepithelial Neoplasia: A Population-based Register Study in Sweden, 2000-2012. Acta Derm Venereol, 2018,99(3):315-320.
[2] KUMAR V, SETHIA KK.Prospective study comparing video-endoscopic radical inguinal lymph node dissection (VEILND) with open radical ILND (OILND) for penile cancer over an 8-year period. BJU Int, 2017,119(4):530-534.
[3] YUAN JB, CHEN MF, QI L, et al.Preservation of the saphenous vein during laparoendoscopic single-site inguinal lymphadenectomy: Comparison with the conventional laparoscopic technique. BJU Int, 2015,115(4):613-618.
[4] SANCHEZ DF, RODRIGUEZ IM, PIRIS A, et al.Clear cell carcinoma of the penis: An unusual and distinctive HPV-Related variant of squamous cell carcinoma: A report of 3 cases. Am J Surg Pathol, 2016,40(7):917-922.
[5] VELAZQUEZ EF, CUBILLA AL.Lichen sclerosus in 68 patients with squamous cell carcinoma of the penis: Frequent atypias and correlation with special carcinoma variants suggests a precancerous role. Am J Surg Pathol, 2003,27(11):1448-1453.
[6] 周翔,秦远.阴茎肿瘤的诊断及手术治疗进展.中华男科学杂志,2018,24(11):1036-1040.
[7] HAKENBERG OW, COMPERAT EM, MINHAS S, et al.EAU guidelines on penile cancer: 2014 update. Eur Urol, 2015,67(1):142-150.
[8] WANG S, DU P, TANG XX, et al.Comparison of efficiency of video endoscopy and open inguinal lymph node dissection. Anticancer Res, 2017,37(8):4623-4628.
[9] KROON BK, HORENBLAS S, LONT AP, et al.Patients with penile carcinoma benefit from immediate resection of clinincally occult lymph node metastases. J Urol, 2005,173(3):816-819.
[10] MICALI G, NASCA MR, INNOCENZI D, et al.Invasive penile carcinoma: A review. Dermatol Surg, 2004,30(s2):311-320.
[11] 王海舟,刘振华,刘健帮,等.阴茎癌原发灶术后即刻腹股沟淋巴结清扫对患者生存的影响.四川大学学报(医学版),2016,47(3):371-375.
[12] BISHOFF JT, BASLER JW, TEICHMAN JM, et al. Endoscopic subcutaneous modified inguinal lymph node dissection (ESMIL) for squamous cell carcinoma of the penis. J Urol, 2003,169(4,S)78.
[13] SINGH A, JAIPURIA J, GOEL A, et al.Comparing outcomes of robotic and open inguinal lymph node dissection in patients with carcinoma of the penis. J Urol, 2018,199(6):1519-1525.
[14] POMPEO A, TOBIAS-MACHADO M, MOLINA WR, et al.Extending boundaries in minimally invasive procedures with simultaneous bilateral video endoscopic inguinal lymphadenectomy (veil) for penile cancer: initial Denver health medical center and ABC school of medicine experience and surgical considerations. Int Braz J Urol, 2013,39(4):587-591.
[15] TOBIAS MM, CORREA WF, REIS LO, et al.Singlesite video endoscopic inguinal lymphadenectomy: initial report. J Endourol, 2011,25(4):607-610.
[16] JORGENSEN MG, TOYSERKANI NM, HYLDIG N, et al.Prevention of seroma following inguinal lymph node dissection with prophylactic, incisional, negative-pressure wound therapy (SEROMA trial): study protocol for a randomized controlled trial. Trials, 2018,19(1):441.
[17] 贺兴,孙家驹,陈天庆,等.负压封闭引流分别结合藻酸盐敷料和医用海绵材料治疗难愈性烧伤创面的效果比较.中国当代医药,2019,26(9):82-84.