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微创泌尿外科杂志  2016, Vol. 5 Issue (1): 22-25    
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精准经尿道膀胱肿瘤切除治疗膀胱侧壁肿瘤的临床研究
郝保良1,2,孙圣坤1,彭亮3,张鹏1,杨国强1,许勇1,徐阿祥1,张磊1,陈光富1,符伟军1,张旭1
1中国人民解放军总医院泌尿外科 100853 北京
2辽阳市中心医院河东新城医院泌尿外科
3中国人民解放军总医院肿瘤内科
Accurate transurethral resection of bladder tumor in the treatment of tumors located in lateral bladder wall
Hao Baoliang1, 2, Sun Shengkun1, Peng Liang3, Zhang Peng1, Yang Guoqiang1,Xu Yong1, Xu Axiang1, Zhang Lei1, Chen Guangfu1, Fu Weijun1, Zhang Xu1,
1Department of Urology, Chinese PLA General Hospial, Beijing 100853, China; 2Department of Urology, Central Hospital of Liaoyang, Hedong New City Branch; 3Department of Oncology, Chinese PLA General Hospial
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摘要 目的:探讨应用等离子针状电极精准切除膀胱侧壁肿瘤的方法及效果。方法:52例膀胱肿瘤患者,肿瘤位于膀胱侧壁,应用等离子针状电极进行精准经尿道膀胱肿瘤切除,记录手术时间、有无诱发闭孔神经反射、有无穿孔、肿瘤病理分期及有无复发等。结果:所有患者均在硬脊膜外麻醉下顺利完成精准经尿道膀胱肿瘤切除,均未进行闭孔神经阻滞。切除侧壁肿瘤62枚,肿瘤大小0.5~4.0 cm,平均(1.75 ± 0.56)cm。单枚肿瘤切除时间1~25 min,平均(11.6±5.7)min。术中均未发生闭孔神经反射,出血少,无膀胱穿孔等并发症,切除的肿瘤均获得完整病理分期:32%为pTa期,55%为pT1期,13%为pT2期。术后随访3~32个月,平均25.6个月,均未见原位肿瘤复发。结论:精准经尿道膀胱肿瘤切除能够完全消除闭孔神经反射,完整切除膀胱侧壁肿瘤,获取完整标本进行精确临床分期。精准经尿道膀胱肿瘤切除是未来膀胱癌精准治疗的重要环节。
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郝保良
孙圣坤
彭亮
张鹏
杨国强
许勇
徐阿祥
张磊
陈光富
符伟军
张旭
关键词 精准经尿道膀胱肿瘤切除膀胱肿瘤针状电极闭孔神经反射    
Abstract:Objective: To investigate the methodology and efficacy of accurate transurethral resection of bladder tumors (ATURBT) located in lateral bladder wall using the plasma needle electrode. Methods: Fifty-two patients with tumors located in the lateral bladder wall received ATURBT with a needle electrode. Parameters including resection time, obturator nerve reflex, perforation, TNM stage, and post-operation recurrence were analyzed. Results: All patients were successfully performed ATURBT under epidural anasthesia without any obturator nerve blockade. Totally 62 tumors were resected with diameter of 0.5-4.0 cm (mean 1.75 ± 0.56 cm). The resection time of one tumor was 1-25 min (mean11.6±5.7 min). No obturator nerve reflex occurred during operation. The minimal blood loss, and no bladder wall perforation occurred. Precise TNM stages were obtained, including 32% pTa, 55% pT1, and 13% pT2. No recurrence at the resection site occurred during a mean (range) follow-up of 25.6 (3-32) months. Conclusions: ATURBT can successfully resect tumors located in the lateral bladder wall without obturator nerve reflex. The "en bloc" specimen helps to make an accurate pathological diagnosis as well as clinical stage. ATURBT represents an important step in accurate bladder cancer treatment.
Key wordsaccurate transurethral resection of bladder tumor    bladder tumor    needle electrode    obturator nerve reflex
收稿日期: 2016-01-03     
ZTFLH:  R737.14  
基金资助:卫生部行业基金子课题(201002010)
通讯作者: 孙圣坤,ssk301@sina.co   
引用本文:   
郝保良,孙圣坤,彭亮,张鹏,杨国强,许勇,徐阿祥,张磊,陈光富,符伟军,张旭. 精准经尿道膀胱肿瘤切除治疗膀胱侧壁肿瘤的临床研究[J]. 微创泌尿外科杂志, 2016, 5(1): 22-25.
Hao Baoliang, Sun Shengkun, Peng Liang, Zhang Peng, Yang Guoqiang,Xu Yong, Xu Axiang, Zhang Lei, Chen Guangfu, Fu Weijun, Zhang Xu,. Accurate transurethral resection of bladder tumor in the treatment of tumors located in lateral bladder wall. JOURNAL OF MINIMALLY INVASIVE UROLOGY, 2016, 5(1): 22-25.
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