1Department of Urology, 2Department of Urology, Institute of Organ Transplantation of PLA, 309th Hospital of PLA, Beijing 100091, China; 2Chinese PLA Medical School, Beijing; 3Department of General Surgery, 309th Hospital of PLA; 4Department of Neurosurgery, 309th Hospital of PLA
Abstract:Objective: To summarize the clinical features, diagnosis and treatment of paraganglioma and to improve clinical recognition, diagnostic and therapeutic level of paraganglioma. Methods: The clinical data of 11 patients with paraganglioma in 309 Hospital of PLA in recent five years, included preoperative examination, diagnosis, preoperative preparation and intraoperative accidents were retrospectively analyzed, and the related literature was reviewed to summarize the key points of diagnosis and treatment. Results: Nine patients were treated surgically. Two cases were successfully treated with retroperitoneal laparoscopic surgery with adequate preparation preoperation. Seven patients had no adequate preparation preoperation in accordance with paraganglioma. Surgical events consisted of conversion from local anesthesia to general anesthesia, conversion to open surgery, massive blood loss, blood transfusion and termination of surgery due to severe fluctuation of blood pressure during the perioperative period. Conclusions: Adequate preparation, close anesthesia monitoring and precise operation during the perioperative period are the key to the treatment of paraganglioma. The skills of vascular surgery for intraoperative vascular injury is critical.
[1]Juan Rosai.回允中主译.阿克曼外科病理学.9版.沈阳:辽宁教育出版社,2006:1117. [2]江昌新,谭郁彬.内分泌器官肿瘤病理学和遗传学.北京:人民卫生出版社,2006:177. [3]王亮,李黎明.副神经节瘤的诊治现状及进展.天津医科大学学报,2013,19(5):430-432. [4]文阳,王华,王伯胤.肾上腺外副神经节瘤的临床特点与CT诊断价值.中国临床医学影像杂志,2009,20(4):286-289. [5]王关顺,刘云霞,廖承德,等.副神经节瘤的CT和MRI表现.中国临床医学影像杂志,2014,25(8):542-546. [6]Somasundar P, Krouse R, Hostetter R, et al. Paragangliomas--a decade of clinical experience. J Surg Oncol, 2000,74(4): 286-290. [7]朱奇,祝宇,张翀宇,等.192例嗜铬细胞瘤/副神经节瘤手术治疗分析.国际泌尿系统杂志,2013,33(3):292-295. [8]高健刚,李汉忠.副神经节瘤的解剖分布与临床特点.中华泌尿外科杂志,2008,29(2):103-106. [9]米军,李怡,王家吉,等.后腹腔镜下行副神经节瘤切除8例报告.中国微创外科杂志,2013,13(12):1094-1097. [10]Wang J, Li Y, Xiao N, et al. Retroperitoneoscopic resection of primary paraganglioma: Single-center clinical experience and literature review. J Endourol, 2014,28(11):1345-1351. [11]文进,李汉忠,纪志刚,等.3D腹腔镜手术治疗肾上腺嗜铬细胞瘤/副神经节瘤的临床研究.中华泌尿外科杂志,2015,36(7):511-513. [12]Xu W, Li H, Ji Z, et al. Comparison of retroperitoneoscopic versus transperitoneoscopic resection of retroperitoneal paraganglioma: A control study of 74 cases at a single institution. Medicine (Baltimore), 2015,94(7):e538. [13]Li G, Qian Y, Bai H, et al. Intertransversalis fascia approach in urologic laparoscopic operations. Arch Surg, 2012,147(2):159-167. [14]Li G, Qian Y, Shi B. "Intertransversalis" approach for laparoscopic urology: Surgical anatomy concerns-reply. Arch Surg, 2012,147(10):980-982.