Abstract：Objective：To compare the efficacy of B-mode ultrasound-guided percutaneous nephroscopic double-channel and laparoscopic un-roofing for simple renal cysts. Methods：Ninety cases of simple renal cyst admitted to our hospital from January 2017 to January 2018 were divided into percutaneous nephroscopy group and laparoscopy group, 45 cases in each group. The general clinical data, surgical conditions, C-reactive protein (CRP), interleukin-6 (IL-6) and procalcitonin (PCT) levels 1 and 3 days after operation were compared between the two groups. Results： There was no significant difference in sex, age, BMI, cyst diameter and cyst location between the percutaneous nephroscopy group and the laparoscopy group. There were 35 cases of lumbar anesthesia, 10 cases of local anesthesia and 45 cases of general anesthesia in the laparoscopy group. Percutaneous nephroscopy group had less bleeding, shorter operation time, shorter extubation time, shorter hospitalization time, lower pain score at 12 h after operation, lower hospitalization cost and fever rate than laparoscopy group. The difference was statistically significant (P<0.05). There was no significant difference in recurrence rate and complication rate between the two groups (P>0.05). The CRP, IL-6 and PCT values in percutaneous nephroscopy group and laparoscopy group increased 1 day after operation and decreased 3 days after operation. The CRP, IL-6 and PCT values in percutaneous nephroscopy group were significantly lower than those in laparoscopy group on 1 and 3 days after operation (P<0.05). Conclusion： Percutaneous nephroscopy is as effective as laparoscopic un-roofing for simple renal cysts, but it has less trauma, shorter hospital stay, lower cost and lower incidence of complications.
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