Abstract:Objective: To investigate the efficacy and safety of flexible ureteroscopic lithotripsy (FURS) for renal staghorn calculi. Methods: From October 2015 to December 2017, 54 cases of renal staghorn calculi treated with FURS were retrospectively analyzed, including 41 cases of partial staghorn calculi and 13 cases of complete staghorn calculi. The Double-J stent was indwelled 2 weeks before lithotripsy. Both dusting and fragmenting techniques were used in the process of lithotripsy. Fragments larger than 2 mm were retrieved using baskets. During the follow-up period of 2 to 4 weeks after surgery, the stone free rate (SFR) was evaluated. If there were residuals of calculi, a second stage of FURS was performed. Results: All patients underwent operation successfully. The average calculi diameter was (34.7 ± 15.7) mm. Among them, 18 patients underwent one-stage FURS, 24 patients underwent 2nd-stage FURS, and 12 patients underwent 3rd-stage FURS. The average procedure of FURS was 1.9 times. The one-stage SFR accounted for 33.3% (18/54), and the overall SFR accounted for 83.3% (45/54). Overall, complication rate was 35.2% (19/54). Among them, there were 8 cases of fever (T>38.5°C); 3 cases of urinary sepsis; 2 cases of ureteral perforation; 4 cases of postoperative stone street, including 1 case of solitary kidney undergoing emergency operation with FURS to remove the stone street, which caused ureter obstruction and acute renal insufficiency; 2 cases of subcapsular renal hematoma. Postoperative hospital stay was 1 to 5 days, with an average of (2.0 ± 1.1) days. Conclusion: The FURS can be used as an ideal option for the treatment of complex staghorn calculi with good efficiency and safety. But the one-stage SFR was relatively low and staged procedures were often necessary to achieve a high SFR.
朱轶勇, 孙丰, 邓铮, 王聪, 邵怡, 鲁军. 输尿管软镜治疗肾脏鹿角形结石的疗效分析[J]. 微创泌尿外科杂志, 2020, 9(4): 226-229.
ZHU Yiyong, SUN Feng, DENG Zheng, WANG Cong, SHAO Yi, LU Jun. Therapeutic effectiveness of flexible ureteroscopy in the treatment of renal staghorn calculi. JOURNAL OF MINIMALLY INVASIVE UROLOGY, 2020, 9(4): 226-229.
[1] BAGLEY DH, HUFFMAN JL, LYON ES. Flexible ureteropyeloscopy: diagnosis and treatment in the upper urinary tract system. J Urol, 1987,138(2):280-285. [2] 杨嗣星,陈志强.软性输尿管镜术中国专家共识.中华泌尿外科杂志,2016,37(8):561-565. [3] TÜRK C, PETŘÍK A, SARICA K, et al. EAU guidelines on interventional treatment for urolithiasis. Eur Urol, 2016,69(3):475-482. [4] ALCALDE ÁF, HERNÁNDEZ MR, SANTOS VD, et al. Comparison between percutaneous nephrolithotomy and flexible ureteroscopy for the treatment of 2 and 3 cm renal lithiasis. Actas Urológicas Españolas (English Edition), 2019,43(3):111-117. [5] ALHUNAIDI O, AHMAD AA, EL-NAHAS AR, et al. Impact of case volume per year on flexible ureteroscopy practice: an internet based survey. BMC Urol, 2019,19(1):134. [6] HYAMS ES, MUNVER R, BIRD VG, et al. Flexible ureterorenoscopy and holmium laser lithotripsy for the management of renal stone burdens that measure 2 to 3 cm--a multi-institutional experience. J Endourol, 2010,24(10):1583-1588. [7] MIERNIK A, WILHELM K, ARDELT P, et al. Standardized flexible ureteroscopic technique to improve stone-free rates. Urology, 2012,80(6):1198-1202. [8] ZUMSTEIN V, BETSCHART P, ABT D, et al. Surgical management of urolithiasis-a systematic analysis of available guidelines. BMC Urol, 2018,18(1):25. [9] EL-NAHAS AR, SHOKEIR AA, EL AA, et al. Postpercutaneous nephrolithomy extensive hemorrhage: a study of risk elements. J Urol, 2007,177(2):576-579. [10] CHEN EH, NEMETH A. Complications of percutaneous procedures. Am J Emerg Med, 2011,29(7):802-810. [11] VORRAKITPOKATORN P, PERMTONGCHUCHAI K, RAKSAMANI EO, et al. Perioperative complications and risk factors of percutaneous nephrolithotomy. J Med Assoc Thai, 2006,89(6):826-833. [12] DE LA ROSETTE J, ASSIMOS D, DESAI M, et al. The clinical research office of the endourological society percutaneous nephrolithotomy global study: indications, complications, and outcomes in 5803 patients. J Endourol, 2011,25(1):11-17. [13] MICHEL MS, TROJAN L, RASSWEILER JJ. Complications in percutaneous nephrolithotomy. Eur Urol, 2007,51(4):899-906. [14] ABOUMARZOUK OM, MONGA M, KATA SG, et al. Flexible Ureteroscopy and Laser Lithotripsy for Stones > 2 cm: A Systematic Review and Meta-Analysis. J Endourol, 2012,26(10):1257-1263. [15] ABOUMARZOUK OM, SOMANI BK, MONGA M. Flexible ureteroscopy and Holmium: YAG laser lithotripsy for stone disease in patients with bleeding diathesis: a systematic review of the literature. Int Braz J Urol, 2012,38(3):298-305. [16] TURNA B, STEIN RJ, SMALDONE MC, et al. Safety and efficacy of flexible ureterorenoscopy and Holmium: YAG lithotripsy for intrarenal stones in anticoagulated cases. J Urol, 2008,179(4):1415-1419. [17] SINGH AG, CHHABRA JS, SABNIS R, et al. Role of flexible uretero-renoscopy in management of renal calculi in anomalous kidneys: single-center experience. World J Urol, 2017,35(2):319-324. [18] LIMA A, REEVES T, GERAGHTY R, et al. Impact of ureteral access sheath on renal stone treatment: prospective comparative non-randomised outcomes over a 7-year period. World J Urol, 2020,38(5):1329-1333. [19] FANG L, XIE G, ZHENG Z, et al. The effect of ratio of endoscope-sheath diameter on intrapelvic pressure during flexible ureteroscopic lasertripsy. J Endourol, 2019,33(2):132-139. [20] VANLANGENDONCK R, LANDMAN J. Ureteral access strategies: pro-access sheath. Urol Clin North Am, 2004,31(1):71-81. [21] DE CONINCK V, KELLER EX, RODRÍGUEZ-MONSALVE M, et al. Systematic review of ureteral access sheaths: facts and myths. BJU Int, 2018,122(6):959-969. [22] L'ESPERANCE JO, EKERUO WO, SCALES CD JR, et al. Effect of ureteral access sheath on stone-free rates in patients undergoing ureteroscopic management of renal calculi. Urology, 2005,66(2):252-255.