Curative effectivensss of transurethral enucleation of prostate for benign prostatic hyperplasia and its effects on BUN, Scr, NSE and S100β protein levels
Yang Jie1, Zhao Hongbo1, Zhao Jinbi1
1Department of Urology, Pingdu People's Hospital, Pingdu 266700, China
Abstract：Objective:To study the curative effectiveness of transurethral enucleation of prostate for benign prostatic hyperplasia and its effects on blood urea nitrogen (BUN), serum creatinine (Scr), NSE and S100β protein levels. Methods:104 patients with benign prostatic hyperplasia from February 2015 to August 2016 in our hospital were selected. Patients were divided into control group and observation group according to factors such as prostate volume, preoperative BUN level, and Scr level, by 1:1 and 52 patients in each group. The control group was treated with TURP transurethral resection of the prostate, and the observation group was treated with transurethral enucleation of the prostate. The operative indexes such as BUN, Scr, NSE, S100β protein levels and complications were compared between the two groups before and after operation. Results:The intraoperative blood loss in the observation group was (177.12±84.38) mL, which was significantly less than that in the control group [(245.29±128.75) mL]; the volume of prostatectomy was (49.62±10.29) mL in the observation, which was significantly greater than that in the control group [(41.14±8.82) mL], and the difference between the two groups was statistically significant (P<0.05). The levels of BUN and Scr in the observation group were (5.59±0.62) mmol/L and (70.28±9.47) μmol/L respectively, which were significantly lower than those in the control group [(5.93±0.77) mmol/L and (78.75±10.28) μmol/L], and the difference between the two groups was statistically significant (P<0.05). The levels of serum NSE and S100β protein were (6.07±2.04) μg/L and (0.15±0.10) μg/L in the observation group after 24 h, and there was no significant difference between the control group and the control group [(6.15±2.08) μg/L and (0.19±0.12) μg/L respectively] (P>0.05). The postoperative hemorrhage, dysuria, urinary incontinence and erectile dysfunction showed no significant difference between the two groups (P>0.05). Conclusions:The curative effectiveness of transurethral enucleation of the prostate for benign prostatic hyperplasia is obvious, and it has little effect on the renal function, does not cause serious damage to the brain tissue, and has good safety.
杨杰, 赵洪波, 赵金碧. 经尿道前列腺剜除术对良性前列腺增生患者的疗效及对BUN、Scr、NSE、S100β蛋白水平的影响[J]. 微创泌尿外科杂志, 2018, 7(5): 338-341.
Yang Jie, Zhao Hongbo, Zhao Jinbi. Curative effectivensss of transurethral enucleation of prostate for benign prostatic hyperplasia and its effects on BUN, Scr, NSE and S100β protein levels. JOURNAL OF MINIMALLY INVASIVE UROLOGY, 2018, 7(5): 338-341.
