Clinical study on the improvement of early micturition dysfunction by the use of nerve electrical regulation in pediatric urology
Ni Zhifu1，Wang Xiaoling2，Qu Zhenfan1
1Department of Surgery, Taihe Hospital, Hubei University of Medicine, Shiyan 442000, China; 2Department of Internal Medicine-Neurology, Taihe Hospital, Hubei University of Medicine
Abstract：Objective: To investigate the clinical values of nerve electrical regulation in the treatment of early micturition dysfunction in pediatric urology. Methods: From January 2014 to February 2016, 120 children in Department of Pediatric Urology of our hospital were selected and studied retrospectively. All the children were equally divided into the observation group and control group by a random number table. Two groups were given conventional surgical treatment, the control group was given conventional bladder training during the operation, and the observation group was given the nerve electrical regulation during the operation. The recovery of postoperative micturition dysfunction was recorded. Results: All the surgical operations were successfully completed. The total effective rate in observation group and control group was 98.3% and 88.3% respectively (P<0.05). After treatment, the frequency of micturition and the number of 24-h urinary incontinence in the observation group were (6.53±1.32) times and (0.89±0.42) times, respectively, significantly less than those in the control group of (8.92±1.41) times and (1.87±0.54) times (P<0.05). There was significant difference in the maximum urethral pressure and filling phase detrusor pressure in the observation group and the control group before and after the treatment (P<0.05), and between two groups after treatment (P<0.05). The incidence of infection, intestinal function change, pelvic hematoma and other complications in the observation group and control group was 10.0% and 8.3% respectively (P>0.05). Conclusions: The neural electrical intervention used in pediatric urology can improve early micturition dysfunction, the maximum urethral pressure and filling phase detrusor pressure, and has better security.
倪志福,汪晓玲,屈振繁. 小儿泌尿外科术中采用神经电调节改善早期排尿功能障碍的临床研究[J]. 微创泌尿外科杂志, 2016, 5(6): 356-360.
Ni Zhifu，Wang Xiaoling，Qu Zhenfan. Clinical study on the improvement of early micturition dysfunction by the use of nerve electrical regulation in pediatric urology. JOURNAL OF MINIMALLY INVASIVE UROLOGY, 2016, 5(6): 356-360.
[1] 沈一丁,唐达星.胎/新生儿膀胱-微小结肠-小肠蠕动功能障碍综合征二例.中华围产医学杂志,2016,19(4):318-320. [2] Herz D, Fuchs M, Todd A, et al. Robot-assisted laparoscopic extravesical ureteral reimplant: A critical look at surgical outcomes. J Pediatr Urol, 2016,7(26):191-197. [3] 郭立华,张谦,范应中,等.索利那新治疗小儿尿道下裂术后膀胱痉挛的疗效分析.中华泌尿外科杂志,2016,37(6):454-457. [4] Sousa AS, Veiga ML, Braga AA, et al. Enuresis and overactive bladder in children: what is the relationship between these two conditions? Int Braz J Urol, 2016,42(4):798-802. [5] 李茂仙,杨屹,侯英,等.单侧肾积水患儿术后肾功能及形态恢复的随访研究.中华泌尿外科杂志,2016,37(6):431-435. [6] Danziger ZC, Grill WM. Dynamics of the sensory response to urethral flow over multiple time scales in rat. J Physiol, 2015,593(15):3351-3371. [7] 郑方芳,刘晓红,莫樱,等.小儿泌尿系统感染与先天性泌尿系统畸形关系的临床分析.中华妇幼临床医学杂志(电子版),2016,21(1):67-70. [8] Su X, Nickles A, Nelson DE. Neuromodulation attenuates bladder hyperactivity in a rat cystitis model. BMC Urol, 2013,6(13):70-78. [9] 刘鑫,刘舸,杨屹,等.儿童双侧肾盂输尿管交界处梗阻性重度肾积水的诊治分析.实用医院临床杂志,2016,13(4):39-43. [10] Chapple C. Therapeutic use of electrical stimulation of peripheral nerves to modulate lower urinary tract function and symptoms. Neurourol Urodyn, 2012,31(8):1205-1209. [11] 王晶,焦永波,刘春茹,等.电针结合膀胱功能训练治疗脊髓损伤后神经源性膀胱的效果.中国医药导报,2016,13(7):87-90. [12] Girard BM, Tompkins JD, Parsons RL, et al. Effects of CYP-induced cystitis on PACAP/VIP and receptor expression in micturition pathways and bladder function in mice with overexpression of NGF in urothelium. J Mol Neurosci, 2012,48(3):730-743. [13] 刘强.探析低频电刺激治疗脊髓损伤后神经源性膀胱尿潴留安全性观察.中国伤残医学,2016,24(14):69-71. [14] Veselá R, Asklund H, Aronsson P, et al. Coupled nitric oxide and autonomic receptor functional responses in the normal and inflamed urinary bladder of the rat. Physiol Res, 2012,61(4):371-380. [15] 伊庆同,吕坚伟,王咏蕾,等.经皮穿刺腹下交感神经阻滞治疗难治性间质性膀胱炎/膀胱疼痛综合征.上海交通大学学报(医学版),2016,36(3):380-384. [16] Cholongitas E, Goulis I, Pagourelias E, et al. Diastolic dysfunction is associated with low urinary sodium excretion in patients with decompensated cirrhosis. Ann Hepatol, 2016,15(5):545-751. [17] 蔡西国,曹留拴,杨阳,等.体表神经电刺激结合间歇导尿训练对脊髓损伤患者尿路感染的影响.中国实用医刊,2016,43(9):83-85. [18] Routh JC, Cheng EY, Austin JC, et al. Design and methodological considerations of the national spina bifida patient registry urologic and renal protocol for the newborn and young child. J Urol, 2016,196(6):1728-1734 . [19] Pacifico L, Bonci E, Andreoli GM, et al. The impact of nonalcoholic fatty liver disease on renal function in children with overweight/obesity. Int J Mol Sci, 2016,17(8):331-339. [20] 钱宝延,蔡西国,马玉娟,等.电针俞募穴治疗脊髓损伤后神经源性膀胱的临床观察.中国康复医学杂志,2016,31(1):50-53. [21] Garcia-Roig M, Arlen AM, Huang JH, et al. Delayed upper tract drainage on voiding cystourethrogram may not be associated with increased risk of urinary tract infection in children with vesicoureteral reflux. J Pediatr Urol, 2016,31(16):187-195. [22] Ebert AK, Lange T, Reutter H, et al. Evaluation of sexual function in females with exstrophy-epispadias-complex: A survey of the multicenter German CURE-Net. J Pediatr Urol, 2016,31(16):149-158.
