Abstract：Objective: To compare the safety and efficacy between flexible ureteroscope lithotripsy (FURL) and percutaneous nephrolithotomy (PCNL) in treating proximal ureteral calculi. Methods: The clinical data of 118 patients who underwent FURL and PCNL for impacted proximal ureteral calculi (diameter＞10 mm) from October 2013 to October 2015 were retrospectively analyzed. Fifty-two patients were treated with FURL and 66 patients were treated with PCNL. The operation time, stone-free rate, perioperative hemoglobin decrease, perioperative WBC, surgical complications rate and length of hospital stay were compared retrospectively between two groups. Results: All the operations were finished successfully. There was no statistically significant difference in stone-free rate and surgical complications rate between the two groups (P>0.05), but the visual analogue scale (VAS) score on the first postoperative day, perioperative hemoglobin decrease, perioperative WBC and length of hospital stay in FURL group were evidently reduced as compared with those in PCNL group (P<0.05). Conclusions: The overall curative effects of FURL and PCNL were similar in treating proximal ureteral calculi. FURL offers less trama, less postoperative pain and quicker recovery time than PCNL, and is worthy of popularization.
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