Comparative analysis of clinical efficacy and security of flexible ureteroscope lithtripsy and percutaneous nephrolithotomy in treatment of patients with renal calculus
Chen Jiabi1,Li Yining1,Zhuang Wei1
1Department of Urology, the Second Affiliated Hospital of Fujian Medical university, Quanzhuo 362000, China
Abstract：Objective: To compare the clinical efficacy and security of flexible ureteroscope lithtripsy vs. percutaneous nephrolithotomy in the treatment of patients with renal calculus. Methods: Totally 110 cases of patients with renal calculus in our hospital from January 2014 to January 2015 were randomly divided into observation group and control group. Control group was given percutaneous nephrolithotomy, and observation group was subjected to flexible ureteroscope lithtripsy. The operation time, stone clearance rate, intraoperative bleeding, hospital stay, the level of serum neutrophil gelatinase-associated lipocalin (NGAL) and complications were compared two groups. Results: There was no significant difference between two groups in the stone clearance rate (P>0.05). The operation time, intraoperative bleeding and hospital stay in observation group were significantly reduced as compared with those in control group (P<0.05). The serum NGAL levels in observation group at 24 h, 48 h and 72 h after treatment were significantly lower than those in control group (P<0.05). There was no significant difference before and 72 h after treatment in observation group in the serum NGAL level (P>0.05). The incidence of renal colic, renal subcapsular hematoma and bacteremia in observation group after treatment was significantly lower than that in control group (P<0.05). Conclusions: Flexible ureteroscope lithtripsy for patients with renal calculus can effectively shorten the operation time and hospital stay, decrease intraoperative bleeding and the serum NGAL level, and reduce the incidence of complications. It is worthy of clinical application.
陈家璧,李毅宁,庄伟. 输尿管软镜碎石术与经皮肾镜碎石术治疗肾结石的临床疗效及安全性比较分析[J]. 微创泌尿外科杂志, 2016, 5(3): 150-153.
Chen Jiabi,Li Yining,Zhuang Wei. Comparative analysis of clinical efficacy and security of flexible ureteroscope lithtripsy and percutaneous nephrolithotomy in treatment of patients with renal calculus. JOURNAL OF MINIMALLY INVASIVE UROLOGY, 2016, 5(3): 150-153.
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