Abstract：Objective:To explore and evaluate the value of preoperative urine white cell(WBC) and C-reactive protein(CRP) in the prediction of infection post-transurethral lithotripsy.Methods:Clinical data of 640 cases underwent transurethral lithotripsy diagnosed as ureteral calculi were collected. Urine analysis and C-reactive protein were tested within 24 hours preoperatively. Relationship between post-operative infection and these parameters was analyzed.Results:Among 640 cases, urine white cell ＜10/HP were observed 509 cases, ＞10/HP were observed 131; CRP＜8 mg/L were observed 481 cases, CRP＞8 mg/L were observed 159; postoperative fever in 68 cases, no fever in 572 cases. No significant difference was found between urine white cell and postoperative fever. Postoperative infection rate with pre-operative CRP＞8 mg/L was significantly higher than those with normal CRP (28.93% versus 4.57%, P＜0.001). In urine WBC＞10/HP, CRP＞8 mg/L subgroup, postoperative infection rate was significantly higher than that in WBC＜10/HP, CRP＞8 mg/L, WBC＞10/HP, CRP＜8 mg/L and WBC＜10/HP, CRP＜8 mg/L subgroups(36.36% versus 26.98% versus 7.14% versus 3.92%, respectively, P＜0.001).Conclusions:Preoperative CRP level ＞8 mg/L was an important predictor of postoperative infection after transurethral lithotripsy. Combining the two parameters can direct the urologist to make the reasonable choice of operation, strengthen the preoperative preparation and reduce the risk of postoperative infection.
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