Abstract：Objective:We prospectively evaluated vaporization efficiency of the high power, 980 nm diode laser for bladder outlet obstruction due to benign prostatic hyperplasia.Methods:A total of 24 consecutive patients recruited in the study between June 2010 and December 2011. The average age was (71.6±3.7) years(57-83 years).The average prostate volume was (68±18) ml (45-105 ml).Patients with a history of neurogenic voiding dysfunction, chronic prostatitis, or prostate or bladder cancer were excluded from analysis. Preoperative maximal flow rate, post-void residual urine, International Prostate Symptom Score and quality of life were compared with values at 3 months. Operation time, bleeding volume, perfusion fluid volume, catheterization time and complications were assessed. Another 34 patients received transurethral plasma kinetic resection of prostate. Data of two groups was studied.Results:Mean operation time of 980 nm laser group was (75.2±28.5) minS, the mean bleeding volume was (10.1±3.2) ml, mean perfusion fluid volume postoperation was (14.1±2.5)L, and catheterization time was (4.1±0.7) days. 4 to 18 months follow-up was performed. Comparing to the 3 months after operation, IPSS score, QOL score, Qmax and PVR had significant improvement(P<0.01).The resection time was longer for 980 nm laser group than PKRP,but the inter-operative bleeding was less in 980nm laser group than PKRP. IPSS, QOL and Qmax were significantly improved after both of the procedures(P＜0.05).Conclusions:980-nm Diode laser vaporesection has the same therapeutic effect as PKRP and less side effects than PKRP. It is a new technology in treatment of symptomatic BPH.
[1]Wendt-Nordahl G, Huckele S, Honeck P, et al.980-nm diode laser: a novel laser technology for vaporization of the prostate.Eur Urol,2007,52(6):1723-1728. [2]Erol A, Cam K, Tekin A,et al. High power diode laser vaporization of the prostate: preliminary results for benign prostatic hyperplasia.J Urol,2009,182(3):1078-1082. [3]Leonardi R, Caltabiano R, Lanzafame S. Histological evaluation of prostatic tissue following transurethral laser resection(TULaR) using the 980 nm diode laser.Arch Ital Urol Androl,2010,82(1):1-4. [4]Leonardi R. Preliminary results on selective light vaporization with the side-firing 980 nm diode laser in benign prostatic hyperplasia:an ejaculation sparing technique. Prostate Cancer Prostatic Dis,2009,12(3):277-280. [5]Szlauer R, Gtschl R, Razmaria A, et al. Endoscopic vaporesection of the prostate using the continuous-wave 2-mm thulium laser: outcome and demonstration of the surgical technique.Eur Urol,2009,55(2):368-375. [6]张西玲,刘春来,刘屹立,等,2 μm激光与等离子双极气化术治疗良性前列腺增生症的疗效比较.中国医科大学学报,2010,39(11):963-964.
