Abstract：Objective:To evaluate the clinical effectiveness of retroperitoneal nephroureterectomy for upper urinary tract urothelial carcinoma.Methods:Between January 2003 and March 2012, clinical data of 103 cases with upper urinary tract urothelial carcinoma, which were treated with retroperitoneal larparoscopic nephroureterectomy, was retrospectively analyzed. Total 94 cases underwent retroperitoneal laparoscopic nephroureterectomy combined with the abdominal incision, whereas the other 9 cases underwent retroperitoneal laparoscopy combined with transurethral resection of ureteric orifice.Results:The operations were completed successfully in all 103 cases. There was no conversion to open surgery. The mean operation time was (165±52) min, the mean blood loss was (125±53)ml. The postoperative hospitalization stay was (6.4±4.1) d.There were no severe peri-operative complications. Pathological examination showed transitional cell carcinoma in all the cases,with Ta 10 cases, T1 43 cases, T2 27 cases, T3 23 cases. During the follow-up of 55(6-90) months, bladder cancer was found in 17 cases, pulmonary metastasis was found in 4 cases. Seven cases died during follow-up, while all of the 4 cases with pulmonary metastasis passed away within 2 year postoperatively.Conclusions:Retroperitoneal laparoscopic nephroureterectomy for upper urinary tract urothelial carcinoma is characterized by short operation time, less bleeding, minimal trauma and quick recovery. The short-period effect is good while the long-term effect needs to be further investigated.
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