Abstract:With evolving local ablation technology, the clinical application of local ablation has been actively investigated in the treatment for renal cell carcinoma. Local ablation has several advantages, including keeping more normal renal units, relatively simple operation, easy tolerance, fewer complications, a shorter hospitalization and convalescence period. Long-term data has determined local ablation is reasonable for poor surgical candidates with renal cell carcinoma; however, tumor size, location and shape might affect the efficacy of ablation. Associated complications appear to be low. Local ablative approaches seem to represent an attractive alternative to extirpative surgery for the treatment of small renal neoplasms in select patients. Potential developments include concepts to improve the accuracy and effectiveness of ablation by improving the guiding, monitoring capabilities and detection capacity of multi-center lesions to provide at least equivalent cancer control to conventional surgery.
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