Abstract:Objective: To investigate the clinical efficacy of ultrasound-guided peritoneal transperitoneal nephroscopic lithotripsy for the treatment of kidney graft stone. Methods: The clinical data of 10 patients with kidney graft calculi treated between July 2018 and September 2022 were retrospectively reviewed.There were 7 males and 3 females with ages ranging from 41-76(54.30 ± 12.13) years.Right kidney graft calculi were present in 6 cases and left kidney graft calculi in 4.There were 3 single pelvic calculi, 1 single ureteral junction calculi, and 6 multiple pelvic calculi, all of which were located in the renal pelvis.The maximum calculi diameter was (2.08 ± 0.51) cm.Calculi CT values were (1364.60±194.11)Hu. Results: All 10 patients underwent transperitoneal percutaneous nephroscopic lithotripsy guided by ultrasound under general anesthesia.Under ultrasound guidance in combination with preoperative CTU, graft puncture sites were determined and appropriate size puncture channels were established.Three Fr 20, five Fr18 and two Fr16 channels were constructed, and calculi fragmentation was performed with holium laser.Calculi-free status, operative time, preoperative postoperative parameters, postoperative complications were observed and recorded.All 10 patients had successful primary surgery and calculi-free procedure.Surgical duration was (59.80±6.46) min.Postoperative hospital stay was(5.60 ± 0.70 )d.There were no sepsis, persistent pain, intraoperative blood transfusion, intestinal duct and mesenteric vascular injury.One patient showed elevated creatinine after operation, which returned to normal after 3 days.After 3 days of surgery, neither color ultrasound nor 1-month repeat computed tomography showed calculi residue, and two J tubes were successfully removed.During the 3-month to 1-year follow-up period,no calculi recurrence occurred and renal function was normal. Conclusion: Ultrasound-guided peritoneal transperitoneal nephroscopic lithotripsy for the treatment of kidney graft calculi is safe and effective.
[1] Henderickx MMEL, Baard J, Wesselman van Helmond PC, et al. Donor kidney lithiasis and back-table endoscopy: a successful combination[J]. Acta Chir Belg, 2021, 31:1-4.
[2] Ferreira Cassini M, Cologna AJ, Ferreira Andrade M, et al.Lithiasis in 1,313 kidney transplants: incidence, diagnosis, and management[J]. Transplant Proc, 2012,44(8):2373-2375.
[3] 谢红昌,易明,丰永花,等. 小体重与大体重儿童供者单供儿童肾移植效果的对比分析[J]. 中华泌尿外科杂志,2021,42(5):370-374.
[4] 张履文,宋彦,费翔. 逆行肾内手术与经皮肾镜取石术治疗嵌顿性输尿管上段结石的疗效比较[J]. 中华泌尿外科杂志,2021,42(7):518-523.
[5] 黄晨,张云龙,阮远,等.融合肾锥体在人体肾脏中的分布及在经皮肾镜通道建立中的临床意义[J].中华腔镜泌尿外科杂志(电子版),2021,15(1):4-7.
[6] 余伟民,曹君,阮远,等.超声引导经肾蒸穹窿-盏颈轴线两步穿刺法”建立经皮肾通道[J].中华腔镜泌尿外科杂志(电子版),2016,10:9-12.
[7] 宋永琳,孙洵,胡伟,等. 输尿管软镜联合钬激光处理移植肾尿路结石7例疗效分析[J]. 现代泌尿外科杂志,2021,26(5):429-431.
[8] Rhee BK, Bretan PN,Stoller ML.Urolithiasis in renal and combined pancreas/renal transplant recipients[J]. J Urol,1999, 161(5): 1458-1462.
[9] Torrecilla Ortiz C, González-Satué C, Riera Canals L, et al.Incidencia y tratamiento de la litiasis urinaria en el injerto renal[J].Actas Urol Esp, 2001, 25(5):357-363.
[10] Sarier M, Duman I, Yuksel Y, et al.Results of minimally invasive surgical treatment of allograft lithiasis in live-donor renal transplant recipients: a single-center experience of 3758 renal transplantations[J]. Urolithiasis, 2019, 47(3):273-278.
[11] Kim H, Cheigh JS, Ham HW.Urinary stones following renal transplantation[J]. Korean J Intern Med, 2001,16(2):118-122.
[12] Fakhr Yasseri A, Saatchi M, Khatami F, et al.The prevalence of renal stones and outcomes of conservative treatment in kidney transplantation: asystematic review and meta-analysis[J].Urol J, 2021, 18(3):252-258.
[13] Malheiro J, Almeida M, Fonseca I, et al.Hyperuricemia in adult renal allograft recipients: prevalence and predictors[J]. Transplant Proc, 2012,44(8):2369-2372.
[14] Cicerello E, Merlo F, Mangano M, et al.Urolithiasis in renal transplantation: diagnosis and management[J]. Arch Ital Urol Androl, 2014,86(4):257-260.
[15] 邓超雄,陈昭颉,王庆堂,等.肾移植后移植肾及输尿管结石七例[J].中华器官移植杂志,2003 ,24(3):147.
[16] Klingler HC, Kramer G, Lodde M, et al.Stone treatment and coagulopathy[J]. Eur Urol ,2003,43(1):75-79.
[17] Del Pizzo JJ, Jacobs SC, Sklar GN.Ureteroscopic evaluation in renal transplant recipients[J]. J Endourol, 1998,12:135-138.
[18] Resorlu B, Oguz U, Resorlu EB, et al.The impact of pelvicaliceal anatomy on the success of retrograde intrarenal surgery inpatients with lower pole renal stones[J]. Urology, 2012, 79(1):61-66.
[19] Wyatt J, Kolettis PN, Burns JR,et al.Treatment outcomes for percutaneous nephrolithotomy in renal allografts[J]. J Endourol,2009,23(11):1821-1824.
[20] 潘生玉,饶婷,程帆,等. 超声引导下经腹腔途径经皮肾镜取石术治疗盆腔异位肾肾结石的疗效分析[J]. 中华泌尿外科杂志,2018,39(9):656-660.
[21] 阮远,李杏,潘生玉,等. 腹腔镜辅助经皮肾镜与输尿管软镜治疗盆腔异位肾结石的临床研究[J]. 中华腔镜泌尿外科杂志(电子版),2019,13(2):80-84.