Expert consensus on bladder tumor endoscopic submucosal dissection
Shi Taoping1, MaXin2, Chen Yongyi3, Hu Xia4, Huang Jian5, Zhu Jie2, Ning Haoyong1, Luo Huarong6, Wu Denglong6, Guo Jianming7, Long Qilai7, Yang Tiejun8, Huang Houbao9, Jiang Junhui10, Fen Hui11, Huang Qingbo2, Zhang Xu2,*
1Hainan Hospital of the PLA; 2General Hospital of the PLA; 3Shaanxi Provincial People’s Hospital; 4Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology; 5Sun Yat-sen Memorial Hospital of Sun Yat-sen University; 6Tongji Hospital of Shanghai, Tongji Hospital of Tongji University; 7Zhongshan Hospital of Fudan University, Shanghai Zhongshan Red Cross Hospital; 8Henan Cancer Hospital, Cancer Hospital of Zhengzhou University; 9the First Affiliated Hospital of Wannan Medical College; 10Ningbo First Hospital, Zhejiang University Ningbo Hospital; 11Pizhou People’s Hospital
Abstract：Bladder cancer is one of the most common malignant tumors of the urinary system. 75% of the patients are newly diagnosed as non muscle invasive bladder cancer. The recommended standard treatment is transurethral resection of bladder tumor （TURBT）, but the recurrence rate is high. In recent years, experts at home and abroad have promoted the concept of “whole block resection”, and bladder tumor endoscopic submucosal dissection （BT-ESD）is rapidly applied clinically. In order to standardize the technology and achieve the purpose of curative resection, domestic experts in related fields of urology and pathology are invited to jointly formulate BT-ESD expert consensus based on domestic and foreign literature and domestic expert experience.
[1] KITAMURA K, KATAOKA K, FUJIOKA H, et al. Transurethral resection of a bladder tumor by the use of a polypectomy snare[J]. J Urol,1980,124(6):808-809. [2] 程永毅,李晶,屈卫星,等.经尿道内镜黏膜下剥离术治疗非肌层浸润性膀胱肿瘤82例疗效分析[J].现代肿瘤医学,2016,24(20):3249-3252. [3] 胡嘏,陈耀兵,杜飞龙,等.经尿道膀胱肿瘤整块切除术标本病理学规范化检查的临床意义[J].中华泌尿外科杂志,2019,40(7):492-497. [4] BALAN GX, GEAVLETE PA, GEORGESCU DA, et al. Bipolar en bloc tumor resection versus standard monopolar TURBT - which is the best way to go in non-invasive bladder cancer?[J] Rom J Morphol Embryol. 2018,59(3):773-780. [5] CHEN X, LIAO J, CHEN L, et al. En bloc transurethral resection with 2-micron continuous-wave laser for primary non-muscle-invasive bladder cancer: a randomized controlled trial[J]. World J Urol,2015,33(7):989-995. [6] LIU H, WU J, XUE S, et al. Comparison of the safety and efficacy of conventional monopolar and 2-micron laser transurethral resection in the management of multiple non muscle-invasive bladder cancer[J]. J Int Med Res,2013,41(4):984-992. [7] D'SOUZA N, VERMA A. Holmium laser transurethral resection of bladder tumor: our experience[J]. Urol Ann,2016,8(4):439-443. [8] CHENG B, QIU X, LI H, et al. The safety and efficacy of front-firing green-light laser endoscopic en bloc photoselective vapo-enucleation of non-muscle-invasive bladder cancer[J]. Ther Clin Risk Manag,2017,13: 983-988. [9] CHENG YY, SUN Y, LI J, et al. Transurethral endoscopic submucosal en bloc dissection for nonmuscle invasive bladder cancer: a comparison study of HybridKnife-assisted versus conventional dissection technique[J]. J Cancer Res Ther,2018,14(7):1606-1612. [10] XU H, MA J, CHEN Z, et al. Safety and efficacy of en-bloc transurethral resection with 1.9 microm vela laser for treatment of non-muscle-invasive bladder cancer[J]. Urology,2018,113: 246-250. [11] ZHANG KY, XING JC, LI W, et al. A novel transurethral resection technique for superficial bladder tumor: retrograde en bloc resection[J]. World J Surg Oncol,2017,15(1):125. [12] HAYASHIDA Y, MIYATA Y, MATSUO T, et al. A pilot study to assess the safety and usefulness of combined transurethral endoscopic mucosal resection and en-bloc resection for non-muscle invasive bladder cancer[J]. BMC Urol,2019,19(1):56. [13] FRITSCHE HM, OTTO W, EDER F, et al. Waterjet aided transurethral dissection of urothelial carcinoma: a prospective clinical study[J]. J Endourol,2011 ,25(10):1599-1603. [14] HURLE R, CASALE P, LAZZERI M, et al. En bloc re-resection of high-risk NMIBC after en bloc resection: results of a multicenter observational study[J]. World J Urol,2020,38(3):703-708. [15] LI K, XU Y, TAN M, et al. A retrospective comparison of thulium laser en bloc resection of bladder tumor and plasmakinetic transurethral resection of bladder tumor in primary non-muscle invasive bladder cancer[J]. Lasers Med Sci,2019,34(1):85-92. [16] 程永毅,孙羿,屈卫星,等.经尿道内镜黏膜下剥离术治疗非肌层浸润性膀胱肿瘤临床分析[J].现代泌尿生殖肿瘤杂志,2015,7(3):136-140. [17] CHEN J, ZHAO Y, WANG S, et al. Green-light laser en bloc resection for primary non-muscle-invasive bladder tumor versus transurethral electroresection: a prospective, nonrandomized two-center trial with 36-month follow-up[J]. Lasers Surg Med,2016,48(9):859-865. [18] NASELLI A, INTROINI C, GERMINALE F, et al. En bloc transurethral resection of bladder lesions: a trick to retrieve specimens up to 4.5 cm[J]. BJU Int,2012,109(6):960-963. [19] NAGELE U, KUGLER M, NICKLAS A, et al. Waterjet hydrodissection: first experiences and short-term outcomes of a novel approach to bladder tumor resection[J]. World J Urol,2011,29(4):423-427. [20] ISLAS-GARCIA JJO, CAMPOS-SALCEDO JG, LOPEZ-BENJUME BI, et al. Surgical technique for en bloc transurethral resection of bladder tumor with a Hybrid Knife®[J]. Actas Urol Esp,2016,40(4):263-267. [21] WANG ZX, ZENG XY, CHEN RB, et al. Free bladder mucosa graft harvested by water-jet: a novel, minimally invasive technique for urethral reconstruction[J]. Exp Ther Med,2018,16(3):2251-2256. [22] GAKIS G, KARL A, BERTZ S, et al. Transurethral en bloc submucosal hydrodissection vs conventional resection for resection of non-muscle-invasive bladder cancer (HYBRIDBLUE):a randomised, multicentre trial[J]. BJU Int,2020,126(4):509-519. [23] 程永毅,孙羿,李晶,等.经尿道内镜黏膜下剥离术治疗非肌层浸润性膀胱肿瘤150例疗效分析:单中心回顾性研究[J].现代泌尿生殖肿瘤杂志,2019,11(4):196-199,204. [24] 朱捷,徐阿祥,陈光富,等.应用海博刀经尿道膀胱肿瘤黏膜下切除术(附41例病例报道)[J].现代泌尿生殖肿瘤杂志,2019,11(4):200-204. [25] ZHANG D, YAO LF, YU S, et al. Safety and efficacy of en bloc transurethral resection versus conventional transurethral resection for primary non muscle-invasive bladder cancer: a meta-analysis[J]. World J Surg Oncol,2020,18(1):4.
