Abstract：Objective： To investigate the difference in efficacy between transurethral holmium laser resection of bladder tumor (THLRBT) and transurethral resection of bladder tumor (TURBT) in the treatment of superficial bladder cancer (SBC) and the effects on urinary function and quality of life. Methods： 105 patients with SBC who underwent surgery combined with bladder perfusion were selected from January 2014 to January 2016. According to the surgical methods, the patients were divided into the TURBT group (63 cases, TURBT) and the THLRBT group (42 cases). The basic data and complications in two groups were compared, and the differences in urinary function and quality of life between two groups were observed before and after surgery. The tumor recurrence and progression in two groups 2 years after surgery were statistically analyzed. Results： The operation time, blood loss, time to get out of bed, indwelling time of catheter and hospital stay in THLRBT group were significantly reduced as compared with those in TURBT group (P < 0.05), and the incidence rate of surgical complications was significantly lower in THLRBT group than in TURBT group (P < 0.05). There was no significant difference in the recurrence rate, progression rate and recurrence time between two groups two years after surgery (P > 0.05). The Qmax and maximum detrusor pressure in THLRBT group were greater than those in TURBT group 1 month after surgery, while the PVR was less than TURBT group (P < 0.05). The quality of life scores in THLRBT group were significantly higher than those in TURBT group 6 month after surgery (P < 0.05). Conclusion： THLRBT is effective in treatment of SBC, which can effectively reduce surgical complications, avoid urinary function injury and improve the quality of life.
白冰, 母健君, 王岭, 高建勇, 郑小敏, 雷弋. 两种经尿道膀胱肿瘤切除术治疗非肌层浸润性膀胱癌的效果对比及对患者生活质量的影响[J]. 微创泌尿外科杂志, 2020, 9(1): 39-43.
BAI Bing, MU Jianjun, WANG Ling, GAO Jianyong, ZHEN Xiaomin, LEI Ge. Efficacy of two transurethral cystectomies for superficial bladder cancer and influence on urination function and life quality. JOURNAL OF MINIMALLY INVASIVE UROLOGY, 2020, 9(1): 39-43.
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