Simultaneous transurethral resection of bladder tumor and benign prostatic hyperplasia in the treatment of non-muscle invasive bladder cancer with benign prostate hyperplasia for the aged patients
Deng Aihua1, Liu Shiwei1, Liu Lifang2
1 Department of Surgery Ⅱ, Jingzhou Fifth People's Hospital 434020, China; 2 Department of Internal Medicine Ⅲ, Jingzhou Fifth People's Hospital;
Abstract:Objective:To evaluate the efficacy of simultaneous transurethral resection of bladder and prostate (TURBT+TURP) in the treatment of non-muscle invasive bladder cancer (NMIBC) with benign prostate hyperplasia (BPH) for the aged patients. Methods:The clinical data of 89 elderly patients with NMIBC and BPH were analyzed retrospectively. Forty-eight patients who underwent TURBT+TURP composed the combination group, and 41 patients who underwent TURP composed the control group. The surgery situation and prognosis were compared. Results:The operative time, blood loss and hospital stays in the combination group were obviously increased as compared with those in control group (P<0.01). After 1 year of operation, both the International Prostate Symptom Score (IPSS) and residual urine volume (PVR) value in the combination group were lower, and the maximal flow was higher than in the control group (P<0.01). After 2 years of operation, the recurrent rate was 2.1% and 17.1% respectively in the combination group and control group and the difference was significant (χ2=6.073, P<0.05). In the combination group, the incidence of urethral stricture was 2.1%, which was lower than that in the control group (17.1%) (χ2=6.073, P<0.01). Conclusions:Simultaneous TURBT and TURP can reduce the postoperative recurrence, relieve difficulty in voiding, decrease incidence of urethral stricture for aged patients with NMIBC and BPH.
邓爱华, 刘世伟, 刘黎芳. 同期经尿道手术治疗非肌层浸润性膀胱癌合并良性前列腺增生患者的临床疗效观察[J]. 微创泌尿外科杂志, 2017, 6(3): 158-161.
Deng Aihua, Liu Shiwei, Liu Lifang. Simultaneous transurethral resection of bladder tumor and benign prostatic hyperplasia in the treatment of non-muscle invasive bladder cancer with benign prostate hyperplasia for the aged patients. JOURNAL OF MINIMALLY INVASIVE UROLOGY, 2017, 6(3): 158-161.
[1] 龚强,朱金海,张小马,等.TURBt联合术后灌注化疗治疗浅表性膀胱癌的疗效分析.安徽医药,2014,18(11):2122-2124. [2] 罗生军,张荣贵,张唯力,等.同期经尿道手术治疗浅表性膀胱癌并前列腺增生对肿瘤复发及种植性转移的影响(Meta分析).临床泌尿外科杂志,2011,26(2):138-140,142. [3] Luo S, Lin Y, Zhang W. Does simultaneous transurethral resection of bladder tumor and prostate affect the recurrence of bladder tumor? A meta-analysis. J Endourol, 2011,25(2):291-296. [4] LI S, Zeng XT, Ruan XL, et al. Simultaneous transurethral resection of bladder cancer and prostate may reduce recurrence rates: A systematic review and meta-analysis. Exp Ther Med, 2012,4(4):685-692. [5] 梁安坡,张玉香,张金庄.尿NMP22及Cox-2蛋白含量检测对浅表性膀胱癌电切术后复发的预判价值研究.海南医学院学报,2015,21(12):1716-1719. [6] 滕志刚,李海波,乔宝民,等.膀胱肿瘤合并前列腺增生手术治疗82例临床分析.天津医科大学学报,2013,19(4):326-328. [7] Dai X, Fang X, Ma Y, et al. Benign Prostatic Hyperplasia and the Risk of Prostate Cancer and Bladder Cancer: A Meta-Analysis of Observational Studies. Medicine (Baltimore), 2016, 95(18):e3493. [8] 张伟,张亚群,崔娣,等.老年人前列腺慢性炎症与前列腺癌及前列腺增生的相关性研究.中华老年医学杂志,2015,34(5):539-542. [9] 石红英.经尿道膀胱肿瘤电切术治疗浅表性膀胱肿瘤的手术的疗效观察.中国卫生产业,2014,5(13):34-35. [10] Babjuk M, Burger M, Zigeuner R, et al. EAU guidelines on nonmuscle- invasive urothelial carcinoma of the bladder: update 2013. Eur Urol, 2013,64(4):639-653. [11] 蔡奕川,李迎东,潘涟春,等.同期经尿道手术治疗浅表性膀胱癌合并前列腺增生的临床疗效观察.国际泌尿系统杂志,2015,35(3):341-344. [12] 谭毅,胡华,程蜀氏,等.经尿道同期治疗浅表性膀胱癌及前列腺增生.四川医学,2012,33(1):103-104.