Abstract：Objective:To evaluate retroperitoneal laparoscopic treatment of enormous pheochromocytoma. Methods:Thirty-nine patients with enormous pheochromocytomas exceeding 6 cm in diameter treated surgically with pathological identification between Jan. 2010 to Sept. 2012 were reviewed retrospectively. Results:The procedure was successful in the 39 cases, and the operation time was 60-120 min with a mean of 75 min. There was no need for blood transfusion with blood loss ranging from 10 to 800 mL. Pheochromocytomas were pathologically proved in all cases, including 3 cases of cystic degeneration and 2 cases of local invasive growth. All patients were followed up for 2-33 months, and there was no recurrence. Conclusions:With improvement of the laparoscopic technique and the development of equipment, retroperitoneal laparoscopy can be considered as the first choice for enormous pheochromocytoma.
[1]Gagner M, Lacroix A, Bolte E. Laparoscopic adrenalectomy in Cushing's syndrome and pheochromocytoma. J New Engl Med, 1992,327(14):1033-1036. [2]Smith CD, Weber CJ, Amerson JR. Laparoscopic adrenalectomy: new gold standard laparoscopic adrenalectomy. J Surg, 1999,23(4):389-396. [3]张旭,叶章群,宋晓东,等.腹腔镜和后腹腔镜肾上腺手术与开放肾上腺手术的疗效比较(附93例报告).中华泌尿外科杂志,2002,23(6):332-334. [4]Gill IS. The case for laparoscopic adrenalectomy. J Urol, 2001,166(2):429-436. [5]Elert A, Olbert P, Hegele A, et al. Accuracy of frozen section examination of testicular tumors of uncertain origin. Eur Urol, 2002, 41(3):290-293. [6]Abboud ER, Coffelt SB, Figueroa YG, et al. Integrin-linked kinase: a hypoxia-induced anti-apoptotic factor exploited by cancer cells. Int J Oncol, 2007.30(1):113-122. [7]Kim JH, Ng CS, Ramani AP, et al. Laparoscopic radical adrenalectomy with adrenal vein tumor thrombectomy:technical considerations. J Urol, 2004, 171(3):1223-1226. [8]Ramacciat OG, Mercantini P, La Torre M, et al. Is laparoscopic adrenalectomy safe and effective for adrenal masses large than 7cm? Surg Endosc, 2008, 22(2):516-521. [9]张旭. 解剖性后腹腔镜肾上腺切除术的手术方法和技巧. 临床泌尿外科杂志,2007,22(8):561-564.
