Abstract:Objective: To evaluate the efficacy of electronic fexible ureteroscopy-holmium laser lithotripsy in treating renal stones in a solitary kidney. Methods: We prospectively enrolled 107 patients with a solitary kidney who underwent electronic fexible ureteroscopy-holmium laser lithotripsy or minimally invasive percutaneous nephrolithotomy (MPCNL) at our hospital between January 2012 to June 2014. Patients were randomly divided into two groups according to the treatment method. The safety, efficacy, and outcome were compared and analyzed. Results: At the first day after the operation catheter was removed. Four weeks after the surgery, KUB or CT was performed to assess the stone excretion rate. The stone-free rate (SFR) (87.0% vs. 90.6%) and operation duration showed no significant difference between two groups (P>0.05), but the bleeding volume (P<0.05). Conclusions: Electronic flexible ureteroscopy-holmium laser lithotripsy is an effective and safe procedure with a lower rate of complication in treating renal stones in a solitary kidney.