Abstract：Objective: To explore the safety and efficacy of two micron laser vaporesection for benign prostatic hyperplasia with coagulation dysfunction. Methods: Respectively, 62 BPH patients with normal coagulation and 56 BPH patients with abnormal coagulation were treated with two micron laser vaporesection. The clinical data preoperation, intraoperation and postoperation were compared and analyed Results: There was no significant difference between the two groups in age, weight of prostate, Qmax and IPSS (P>0.05). In the two groups, no severe hemorrhage, transurethral resection syndrome and damage of rectum occurred. In the normal coagulation group, the mean time of operation was (69.1±12.0) min, the mean blood loss during operation was (62.5±8.9) mL, the mean time of bladder irrigating after operation was (9.0±1.7) h, the mean Qmax at 3rd month postoperation was (20.3±2.8) mL/s and the mean IPSS at 1st month postoperation was (7.2±1.3). In the abnormal coagulation group, the mean time of operation was (69.7±15.8) min, the mean blood loss during operation was (64.5±10.9) mL, the mean time of bladder irrigating after operation was (9.5±2.4) h, the mean Qmax at 3rd month postoperation was (19.7±2.6) mL/s and the mean IPSS at 3rd month postoperation was (7.7±3.3). There was no significant difference between the two groups in operation time, blood loss, bladder irrigating time, Qmax and IPSS (P>0.05). Conclusions: Two micron laser vaporesection of the prostate is a safe and effective treatment for BPH with coagulation dysfunction.
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