Abstract：Objective： To investigate the curative effect of different microsurgical methods for varicocele. Methods： 90 patients with varicocele were randomly divided into two groups, with 45 cases in each group. The control group was treated with ligation of the spermatic vein via inguinal by microscope and observation group was treated with ligation of spermatic vein by microscope through inguinal ring. The operation time, blood loss, postoperative Visual Analogue Score (VAS), postoperative complications and recurrence of two groups were recorded. The semen quality and sex hormone levels of two groups were measured before and 6 months after surgery. Results： The operation time of observation group was longer than control group, but the length of hospital stay and postoperative VAS score were all lower than those of control group (P<0.05). Compared with preoperative group, the sperm density, viability and a+b level sperm percentage of two groups were significantly improved after surgery , and the semen parameters of observation group were better than those of control group (P<0.05). After surgery, the serum testosterone (T) level of observation group was significantly higher than that of control group, while the serum follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels were lower than those of control group (P<0.05). There was no statistically significant difference between two groups in postoperative complications at 1 year after surgery (P>0.05). The recurrence rate of observation group was significantly lower than that of control group (P<0.05). Conclusion： The ligation of spermatic vein by microscope through inguinal ring is effective in the treatment of varicocele. It can effectively improve the quality of patients' semen, promote the recovery of sexual hormone level, and has high safety.
