Abstract：Objective: To retrospectively study the risk factors of systemic inflammatory response syndrome (SIRS) in patients with double J tube after ureteroscopic lithotripsy in order to provide effective evidence for clinical prevention of SIRS. Methods: A data collection form designed was used to collect the clinical data of patients with double J tube after ureteroscopic lithotripsy in Department of Urology of the First People's Hospital of Yunnan Province from January 2014 to January 2015, and patients were divided into two groups according to whether SIRS occurred after surgery, then univariate and multivariate logistic regression analyses were conducted to explore the risk factors of SIRS. Results: A total of 192 patients (125 males and 67 females) were included, and 5.7% (11/192) patients had SIRS appearance. Univariate analysis indicated that infection (P=0.043), renal malformation (P=0.008) and serum creatinine levels (P=0.006) were significantly different between two groups. Multivariate retrospective analysis revaled that renal malformation (P=0.025) was an independent risk factor of SIRS. Conclusions: Renal malformation increases the risk of SIRS in patients with double J tube after ureteroscopic lithotripsy, and reoperative examination should be performed to prevent the occurrence of sepsis caused by SIRS.
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