Abstract：Objective:To investigate the feasibility and efficacy of treatment for 16 interstitial cystitis cases with transurethral intravesical nerve block injection.Methods:Between July 2010 and November 2011,16 interstitial cystitis cases who presented with urinary urgency and frequency or pelvic and perineal pain were analysed, the pathology was confirmed as interstitial cystitis with cystoscopy preoperatively,all cases had strong indication of surgery, using transurethral intravesical nerve block injection treatment with trigone injection of anesthetic and glucocorticoid drugs and comparative analysing the patients pain index score and interstitial cystitis symptoms and distress index score changes before and after surgery.Results:Two weeks after surgery, all patients' a 24-hour voiding and nocturia frequency decreased significantly, bladder capacity increased significantly compared with the preoperative, the pain scores and cystitis symptom index, interstitial cystitis plagued index decreased significantly compared with the preoperative, the differences were statistically significant (P<0.01). The postoperative patients were not seen a large number of hematuria, infection or other complications.Conclusions:Transurethral intravesical nerve block injection may be a new method treating for interstitial cystitis, which is effective and feasible, but its long-term safety and efficacy remains to be further confirmed.
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