Abstract:Objective: To summarize the clinical operative technique and effect of totally robotic-assisted laparoscopic radical cystectomy (tRARC) with orthotopic ileal neobladder by da Vinci surgical system. Methods: From Mar 2012 to July 2015, 9 male patients of bladder urothelial carcinomas underwent tRARC with orthotopic ileal neobladder were enrolled. The mean age was 54 years (ranged from 37-64 years). All patients were diagnosed preoperatively with muscle-invasive or high-grade bladder urothelial carcinomas in cystoscopic biopsy. There were no adjacent organ infiltration found, pelvic lymph node metastases or distant metastasis on preoperative examinations, and the clinical stage were all below T3N0M0. General anesthesia was administered for tRARC with intracorporeal orthotopic ileal neobladder to all patients. Results: All 9 cases were successful. The average operation time was 520min (ranged from 360-780 min) with average blood loss of 555ml (300 to 1 200 ml), and the average number of lymph nodes was 13 (ranged from 4 to 23). All patients resumed ambulation on postoperative 2 to 3 days, and bowel function recovered on either postoperative day 3 or 4. The average length of hospital stay was 20d (ranged from 10-32 d). One month after operation a cystogram was performed to confirmed watertight healing. During the follow up of 3-43 months (mean 30 months ). All of the patients have normal renal functions and satisfactory urinary continence without hydronephrosis. Conclusions: According to the initial surgery procedure and the results of the initial operation, the tRARC with intracorporeal orthotopic ileal neobladder by da Vinci surgical system is feasible in clinic. More基金项目:国家高技术研究发展计划(863计划)(2012AA021100) operational experience, standard surgical procedures, long-term and randomized controlled studies will be helpful to evaluate and promote the technology.
[1]Babjuk M, Burger M, Zigeuner R, et al. EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder: update 2013. Eur Urol, 2013, 64(4): 639-653. [2]Lawrentschuk N, Colombo R, Hakenberg OW, et al. Prevention and management of complications following radical cystectomy for bladder cancer. Eur Urol, 2010, 57(6): 983-1001. [3]Gandaglia G, De Groote R, Geurts N, et al. Oncologic Outcomes of Robot-Assisted Radical Cystectomy: Results of a High--Volume Robotic Center. J Endourol, 2015, Epub ahead of print. [4]Collins JW, Sooriakumaran P, Sanchez-Salas R, et al. Robot-assisted radical cystectomy with intracorporeal neobladder diversion: The Karolinska experience. Indian J Urol, 2014, 30(3): 307-313. [5]朱捷,高江平,徐阿祥,等.机器人辅助腹腔镜根治性膀胱切除体外尿流改道术.中华外科杂志,2009,47(16): 1242-1244. [6]Bochner BH, Dalbagni G, Sjoberg DD, et al. Comparing open radical cystectomy and robot-assisted laparoscopic radical cystectomy: a randomized clinical trial. Eur Urol, 2015, 67(6): 1042-1050. [7]Abraham JB, Young JL, Box GN, et al. Comparative analysis of laparoscopic and robot-assisted radical cystectomy with ileal conduit urinary diversion. J Endourol, 2007, 21(12): 1473-1480. [8]Canda AE, Atmaca AF, Altinova S, et al. Robot-assisted nerve-sparing radical cystectomy with bilateral extended pelvic lymph node dissection (PLND) and intracorporeal urinary diversion for bladder cancer: initial experience in 27 cases. BJU Int, 2012, 110(3): 434-444. [9]Gamboa AJ, Young JL, Dash A, et al. Pelvic lymph node dissection and outcome of robot-assisted radical cystectomy for bladder carcinoma. J Robot Surg, 2009, 3(1): 7-12. [10]Ahmed K, Khan SA, Hayn MH, et al. Analysis of intracorporeal compared with extracorporeal urinary diversion after robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium. Eur Urol, 2014, 65(2): 340-347. [11]Beecken WD, Wolfram M, Engl T, et al. Robotic-assisted laparoscopic radical cystectomy and intra-abdominal formation of an orthotopic ileal neobladder. Eur Urol, 2003, 44(3): 337-339. [12]Fahmy O, Asri K, Schwentner C, et al. Current status of robotic assisted radical cystectomy with intracorporeal ileal neobladder for bladder cancer. J Surg Oncol, 2015, 112(4): 427-429. [13]Shao P, Li P, Ju X, et al. Laparoscopic radical cystectomy with intracorporeal orthotopic ileal neobladder: technique and clinical outcomes. Urology, 2015, 85(2): 368-373. [14]陈光富,瓦斯里江·瓦哈甫,马鑫,等.完全腹腔镜下根治性膀胱全切除加原位回肠新膀胱术(附3例报告).临床泌尿外科杂志,2012, 27(8):601-604.