1Department of Radiology in South Building, Chinese PLA General Hospital, Beijing 100853, China; 2Department of Radiology, Chinese PLA General Hospital
Abstract：Objective:To retrospectively assess the diagnostic performances of ADC value on nodular and diffusely growing prostate cancers for prostate cancers in peripheral zones. Methods:Two readers retrospectively evaluated the ADC values of 35 cases of pathologically proven prostate cancer and 22 cases of pathologically proven non-cancerous diseases in peripheral zones. Results:For reader 1 and reader 2, the AUCs for nodular prostate cancer diagnoses in peripheral zones were 0.713 (95% CI: 0.566, 0.866) and 0.748 (95% CI: 0.605, 0.890) respectively, and 0.943 (95% CI: 0.854, 1.033) and 0.876 (95% CI: 0.729, 1.023) for diffusely growing prostate cancer diagnoses in peripheral zones. When cut-off value of ADC was set to 1.02×10-3 mm2/s, the diagnostic accuracies of ADC value on these two shapes of prostate cancers in peripheral zone were 67.4% to 70.5% and 84.0% to-85.7% respectively. Conclusions:The diagnostic performances of ADC was relative good on diffusely growing prostate cancers and mean on nodular prostate cancer in peripheral zones.
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