Treatment and follow-up of multilocular cystic renal cell carcinoma by laparoscopic nephron sparing surgery: A report of 17 cases
XIAO Jun1, YU Gan1, YANG Chunguang1, HU Henglong1, WANG Jing1, ZANG Yu1, CHEN Liang1, GUO Liang2, WU Jian3, WANG Shaogang1, HU Zhiquan1, YE Zhangqun1, WANG Zhihua1
1Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of cience and Technology, Wuhan 430030, China; 2Department of Urology, Lu'an Hospital, Anhui Medical University; 3Department of Urology, Duchang County People's Hospital
Abstract:Objective: To study the clinical features and surgical treatment strategies of multilocular cystic renal cell carcinoma and to provide the evidence for clinical diagnosis and treatment. Methods: The clinical manifestations, imaging features, histopathological features, surgical treatment and follows-up of 17 patients with multilocular cystic renal cell carcinoma undergoing laparoscopic (or robot-assisted laparoscopic) partial nephrectomy and admitted to the Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology from March 2013 to March 2018 were studied retrospectively. Results: The postoperative pathological examinations of all 17 patients undergoing partial nephrectomy confirmed the diagnosis of multilocular cystic renal cell carcinoma. The follow-up period was 3 to 52 months (mean 35.0±13.7 months). The renal function of the patients was normal after the operations. Sixteen patients had no recurrence and the clinical symptoms disappeared. One patient had a CT examination after 9 months, displaying the tumor was relapse at 9th months, and accepted radical nephrectomy and retroperitoneal lymph node dissection. Renal clear cell carcinoma with retroperitoneal lymph node metastasis was diagnosed pathologically. Conclusions: The multilocular cystic renal cell carcinoma is often identified by physical examination. The imaging findings are relatively special and need to be carefully distinguished. The laparoscopic partial nephrectomy can successfully complete the operation, with the advantages of more minimal invasion and less postoperative complications.
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