目的:探讨头孢曲松钠相关性药物性结石引起急性肾功能衰竭的微创治疗。方法:回顾性分析2013年10月~2016年10月应用头孢曲松钠治疗后发生急性肾功能衰竭13例患者的临床资料,其中男5例,女8例,平均34岁。肾功能平均Cr 384 μmol/L,BUN 12.3 mmol/L。急诊行膀胱镜下留置输尿管支架管。结果:13例患者均顺利留置输尿管支架管,手术治疗后30 min~1 h内尿液平均为1 500 ml。2~3 d后肾功能均恢复正常。结论:头孢曲松钠相关性药物性结石引起急性肾功能衰竭,应尽快解除梗阻,恢复肾功能,同时要规范使用头孢曲松钠。

Objective: To explore the minimally invasive treatment of acute renal failure associated with ceftriaxone sodium-related drug calculi.Methods: Thirteen cases of acute renal failure caused by deftriaxone sodium-related drug calculi were retrospectively analyzed in our hospital from October 2013 to October 2016. There were 5 males and 8 females with mean age of 34 years. The mean serum creatinine level was 384 μmol/L and mean urea nitrogen was 12.3 mmol/L. Indwelling of ureteral stents by bladder scope was done.Results: All 13 patients were successfully subjected to indwelling of ureteral stents. Thirty min to 1 h after operation, the average urine was 1 500 mL. After 2-3 days, renal function was normal.Conclusions: In acute renal failure caused by ceftriaxone sodium-related drug calculi, ureteral obstruction should be relieved as soon as possible, renal function recovers, and simultaneously, ceftriaxone sodium should be used normatively.